Medical Science Liaison-New York

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal's medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Medical Science Liaison, Endocrinology

The Medical Science Liaison, Endocrinology (MSL) is a field-based medical role focused on building and maintaining scientific partnerships with healthcare professionals (HCPs) and key decision-makers through non-promotional, evidence-based scientific exchange. The MSL will serve as a key liaison for Madrigal's clinical and scientific efforts in MASH/NASH, engaging thought leaders (TLs), academic centers, community practices, and regional organizations to support disease education, clinical research, and launch readiness.

Key Responsibilities

• Establish Madrigal's presence and scientific leadership in MASH/NASH and chronic liver disease.

• Identify, develop, and maintain long-term collaborations with TLs, clinical investigators, and key stakeholders within the assigned geography.

• Deliver peer-to-peer, scientifically balanced exchanges on MASH/NASH disease state and Madrigal's clinical programs and investigational therapies.

• Serve as a scientific expert to internal stakeholders, contributing to launch planning, field-based insights, and development of medical communication strategies.

• Provide scientific and strategic input for investigator-initiated trials, research collaborations, and site support in partnership with Clinical Development.

• Facilitate internal scientific training and contribute to speaker programs, advisory boards, and other medical affairs activities.

• Represent Madrigal at national and regional scientific and medical conferences, supporting booth activities and engaging with HCPs to capture real-world insights.

• Respond compliantly to unsolicited medical information requests, ensuring documentation aligns with internal processes and regulatory standards.

• Maintain strict compliance with applicable laws, industry codes, and company policies, with a strong grasp of US healthcare and regulatory environments.

Qualifications

• Advanced degree in a scientific or healthcare discipline (e.g., MD, DO, PharmD, PhD, DNP, PA-C).

• Minimum 3 years of previous MSL experience in a pharmaceutical or biotech industry, preferably in a field-based medical role. Prior experience in Endocrinology preferred. Postdoctoral, academic, or government experience may be considered.

• Solid knowledge of clinical medicine, disease management, and medical research, ideally within hepatology or gastroenterology.

• Strong understanding of the US healthcare system, care delivery, and payer environment.

• Familiarity with FDA regulations, ICH/GCP guidelines, and legal considerations relevant to medical affairs and research.

• Proven ability to synthesize and communicate complex scientific data clearly and concisely to diverse audiences.

• Excellent project management, collaboration, and communication skills.

• Highly motivated and adaptable team player with the ability to work cross-functionally across commercial, clinical, and access teams.

• Proficient in digital tools including CRM platforms, Microsoft Office Suite, and virtual collaboration tools.

• Willingness to travel extensively (~60-70%), including occasional weekend commitments for scientific meetings.

#LI-Remote

Madrigal's Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate's qualifications, skills, education, experience, business needs and market demands. The base salary range for this position is $195,300 - $238,700 per year.

All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com.

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals' Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal's name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to HR@madrigalpharma.com.