Senior Research Asscociate, Biology- Temporary

Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing advancements in genetics, immunology and neuroscience, we are pioneering the development of potential therapies to counteract the devastating progression of neurodegeneration. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history.

Alector is seeking a Senior Research Associate (SRA) in Biology to join our dynamic team. This SRA will be responsible for conducting in vitro studies and analytical assays to evaluate potential therapeutics for neurodegenerative diseases. This role will involve in vivo and in vitro sample processing for downstream biochemical assessments, assisting in cellular and animal studies, and maintaining accurate records to support PK/PD, efficacy, safety, POC, and MOA studies.

Core Job Responsibilties

• Perform in vitro pharmacology studies in IPSC-derived cellular models (iNeurons, iMicroglia, co-and triple-culture systems)
• Collect and process biological samples (cell lysates, media, rodent brain, and other organs) for downstream analysis.
• Assist in the development and optimization of cellular disease models, including Alzheimer's disease, POC, MOA models.
• Maintain accurate records of experiments, protocols, and data in electronic lab notebooks (ELN).
• Collaborate daily with cross-functional teams, including Biology, ADPE, and Preclinical groups.

We'd love to hear from you if:

• BS/MS in Neuroscience, Immunology, Biology, or a related field with 2+ years of industry research experience.
• Hands-on experience with cell culture techniques, IPSC and primary rodent neuronal cell models
• Experience with immunoblotting, ELISA, MSD, ICC, FACs, IHC
• Familiar with confocal microscopy, neurohistology techniques
• Proficient in Word, Excel, PowerPoint, and GraphPad Prism.
• Excellent organizational and communication skills.
• Strong attention to detail.
• Highly adaptable and capable of adjusting to shifting priorities.
• Able to work in a fast-paced and highly collaborative environment.

$55 - $65 an hour

Hourly ranges will be determined by the candidate's level, qualifications, skill set, and experience.

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At Alector, our vision is bold, people are our priority, and our values are at the core of everything we do. Our dynamic and flexible environment encourages our teams to experiment, take ownership of decisions, and question convention to solve complex problems. We value shared wins, perseverance, and a growth mindset, which drives us forward, together.

Among the things you'll discover at Alector from your very first day are our committed and driven colleagues, a bold company vision, and new, modern offices designed to inspire innovation and collaboration in South San Francisco, right at the heart of Biotech Bay. Our benefits are thoughtfully designed around Alectorians and their loved ones and include flexible hybrid work options, competitive compensation, and comprehensive and unique benefits that enhance your health and well-being. Come join us!

We believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other's assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, perform essential job functions, and receive other benefits and privileges of employment. Please contact us to request accommodation.

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