Director, Data Science

Rhythm PharmaceuticalsBoston, MA

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Job Description

Company OverviewRhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.Job SummaryWe are seeking a highly motivated and experienced Director of Data Science to lead data-driven initiatives in support of our clinical, regulatory, and scientific objectives. The successful candidate will have a strong background in biostatistics, genetics, and data analytics, and will be responsible for developing and implementing advanced data models, predictive tools, and integrative analyses across the obesity and metabolic disease therapeutic area. This role will work collaboratively with key inter-disciplinary stakeholders (e.g. biostatistics, clinical development and regulatory affairs) to drive the generation of actionable data insights to support enterprise-wide goals and initiatives. This position offers the opportunity to shape data strategy at a growing biotech and directly impact research, development, and regulatory decision-making.Responsibilities and Duties

Lead the design, development, and implementation of data analysis pipelines, predictive models, and statistical frameworks to support research, clinical, and regulatory programs.
Partner cross-functionally with Biostatistics, Clinical, Regulatory, and Market Access teams to ensure data insights align with organizational priorities.
Oversee data processing, curation, and integration from clinical trials, biomarker studies, and external datasets.
Translate complex data outputs into actionable insights to inform publications, protocol development, and regulatory submissions.
Ensure data quality, reproducibility, and compliance with company and industry standards.
Provide scientific and technical leadership for the use of statistical genetics, machine learning, and advanced analytics in biomarker and outcomes research.
Mentor and guide junior scientists and analysts in the use of SQL, Python, and R for statistical modeling, data visualization, and automation.
Collaborate with internal and external stakeholders to drive innovation in data science applications and contribute to the company’s broader data strategy.

Qualifications and Skills

Ph.D. in Biostatistics, Computational Biology, Genetics, Data Science, or related quantitative field.
8+ yearsof industry experience in biotechnology, pharmaceuticals, or healthcare analytics, with demonstrated leadership in cross-functional projects.
Experience with obesity/metabolic-related biology and datasets
Strong programming and data manipulation skills in SQL, Python, and R.
Proven expertise in biostatistics, statistical genetics, and predictive modeling.
Experience integrating and analyzing clinical trial and biomarker datasets.
Experience handling population-scale genomics datasets (e.g., UKB, AoU); familiarity with the ACMG classification system; statistical analysis of rare variants.
Familiarity with real-world data, electronic medical records, omics analysis, and data visualization platforms.
Excellent communication skills with the ability to translate data findings into strategic insights for diverse stakeholders.
Demonstrated ability to work independently, prioritize effectively, and deliver high-quality results under deadlines.
Track record of innovation, scientific rigor, and collaboration across multidisciplinary teams.
Leadership experience in a matrixed environment or managing small teams.

This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs.This role may involve some travel.More about Rhythm We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause. Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism. At Rhythm our core values are:

We are committed to advancing scientific understanding to improve patients’ lives
We are inspired to tackle tough challenges and have the courage to ask bold questions
We are eager to learn and adapt
We believe collaboration and ownership are foundational for our success
We value the unique contribution each individual brings to furthering our mission

Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law. Headquartered in Boston, Rhythm is proud to have been named one of the Top Places to Work in Massachusetts.

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