Director, Neurobiology - Target Validation And Drug Discovery
Valo HealthLexington, MA
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Job Description
What You'll Do…
- Develop strategies and validation platforms that may be used to validate novel targets.
- Serve as research project lead on various stage preclinical drug discovery projects.
- Lead and mentor a team of scientists dedicated to cell model development for target validation and support of biology goals in drug discovery programs.
- Serve as a subject matter expert in Parkinson's disease and other neurodegenerative diseases mechanisms involved in immune and other CNS-relevant cell type dysregulation
- Provide thought leadership and guidance on CNS disease-relevant assays, staying abreast of emerging trends and advancements in the field.
- Generate hypothesis-driven experimental plans and proposals for target validation in close collaboration with data scientists and other subject matter experts to enable crisp decision making.
- Manage scientists (direct report) and teams in a matrixed manner to ensure high-quality data generation and timely delivery of key readouts supporting team goals.
- Design experiments to coordinate and manage with CROs.
- Work in collaboration with Valo's tissue and cell model experts to support target validation projects as well as ongoing drug discovery projects.
What You Bring...
- A PhD in Biological Sciences or a related field with 10+ years of experience (which may include postdoctoral experience), MS with 14+ years, or BS with 16+ years and deep expertise in Parkinson's disease, human cell assay/model development, and immunology/neuroinflammation.
- Expertise in in vitro systems including cell culture, molecular biology, genetic manipulation, and development of functional assays.
- Experience leading early and established preclinical stage drug discovery programs.
- Experience managing and collaborating with teams and scientists in a matrixed fashion to produce high-quality data.
- Track record of impactful scientific contributions as demonstrated by high impact publications and prior success in progressing programs through a therapeutic pipeline.
- Strong oral and written communication, presentation and interpersonal skills.
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Submit 10x as many applications with less effort than one manual application.