Lead Security Engineer

POSITION LOCATION: San Francisco Bay Area, Remote candidates within the U.S. are strongly encouraged to

apply.

POSITION SUMMARY:

We are building a forward-looking cybersecurity team and are seeking a highly skilled,

technology-savvy, hands-on and result driven Lead Security Engineer to join our high-

performing team. This is a key role in shaping our AI First Security Transformation

strategy to protect Natera future systems across AWS, GCP, Networks, OT, and SaaS.

In this dynamic, fast-paced environment, you will be responsible for designing,

implementing, and automating secure, scalable solutions across cloud, containerized,

and on-premises environments. You will use the latest technologies to develop security

solutions to enhance Natera's security posture.

To be successful in this role, deep understanding of security controls across multiple

domains and solid hands-on experience in security automation are must have. Besides

solid cybersecurity domain knowledge, the candidate should be proficient in Python,

Java, and other comparable automation languages, expert level experience in AI

assisted programming and automation, to drive cybersecurity operational efficiency.

As the outcome, this position will deliver the secure automation and integration across

different platforms and clouds, while ensuring alignment with enterprise security

standards. Collaboration with cross-functional teams is essential to embed security

across the entire technology stack.

PRIMARY RESPONSIBILITIES:

● Lead the development and implementation of enterprise-wide security automation

strategies and frameworks

● Design, build, and run security automation solutions for AWS and on-premises

environments, with a strong emphasis on Zero Trust principles, identity and access

management (IAM), encryption, secure access controls, SIEM and XDR platforms.

● Partner with Engineering, DevOps, IT, and Compliance teams to ensure security

automation adoption and security-by-default principles are embedded into

infrastructure and applications

● Collaborate with DevOps and engineering teams to embed security automation into

CI/CD workflows and Infrastructure-as-Code (IaC) processes

● Establish and enforce security best practices in containerized environments (e.g.,

EKS, ECS) and AI-enabled applications, including workload protection, runtime

monitoring, and secrets management.

● Support the secure design, development, and deployment of AI/ML solutions and

data pipelines, ensuring robust controls around model access, training data, and

infrastructure

● Champion the use of security automation and playbooks using tools such as Python,

Lambda, Terraform, and others to streamline security testing, threat detection, and

remediation workflows.

● Evaluate and recommend security tools, platforms, and automation approaches that

align with business goals and security requirements.

● Work closely with the Incident Response team to ensure security automation is

enabled to efficiently address the current and emerging threat landscapes.

● Participate in design reviews, conduct threat modeling exercises, and contribute to

architecture governance and decision-making processes.

● Influence the development of security policies and standards to align with industry

best practices and regulatory frameworks (e.g., HIPAA, NIST, CISA, FDA).

● Stay current on industry trends, emerging threats (including AI-driven threats), and

technologies to continuously enhance the organization's security posture.

● Mentor and provide guidance to security engineers and developers on security

automation and related AI technologies.

QUALIFICATIONS:

● Bachelor's degree in Computer Science, Information Security, Engineering, or a

related field required

● Master's degree in Computer Science, specifically in Information Security or a

related discipline is strongly preferred

● Minimum of 12 years of progressive experience in cybersecurity, including at least 5

years in a security engineering/automation or senior-level engineering role

● Hands-on experience with security automation is a must have, along with proficiency

in AI assisted development, familiar with Python, Cursor, Lambda, Terraform, or a

comparable scripting and infrastructure-as-code (IaC) tool, to drive security

operational efficiency and consistency.

● Deep experience in design, implement, and run large scale enterprise solutions

(ideally in Healthcare or financial sectors)

● Proven ability to design and implement security controls aligned with compliance

frameworks such as HIPAA, NIST, and CIS.

● Extensive hands-on experience in AWS cloud security, network security, with

extended knowledge on Zero Trust, Data Protection, and Appsec

● Strong understanding of enterprise identity and access management (IAM) systems,

Data Protection, including platforms like Okta, SailPoint, VDI, and Active Directory

(AD).

● Expert experience with SIEM platforms, XDR, and cloud-native threat detection

tools.

● Expert experience in web application security, OWASP, API security, and secure

design and testing

● Industry certifications preferred: CISSP, CCSP, AWS Certified Security- Specialty,

AWS Certified Solutions Architect- Professional, or AWS Certified Advanced

Networking- Specialty (or equivalent).

KNOWLEDGE, SKILLS, AND ABILITIES:

● Excellent written and verbal communication skills, able to translate complex security

concepts for technical and non-technical audiences.

● Ability to influence stakeholders and drive alignment across multiple teams.

● Strategic thinker with a passion for security innovation, continuous improvement, and

building scalable defenses.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

San Carlos, CA

$172,400-$215,450 USD

OUR OPPORTUNITY

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits- Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:

• BBB announcement on job scams
• FBI Cyber Crime resource page