Manager, Master Data Management

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!  

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. 

Why Join our IT team? 

• Innovative Environment: Leverage the latest technologies to drive digital transformation in cancer immunotherapy. From cloud platforms to advanced data solutions, your expertise will help build the backbone that powers groundbreaking science. 

• Collaborative Culture: Work alongside scientists, engineers, and global IT experts in a truly cross-functional setting. You’ll have the opportunity to share ideas, solve complex challenges, and grow your technical and leadership skills in a supportive environment. 

• Global Impact: Your IT solutions will enable researchers and clinicians worldwide to work faster, smarter, and more securely. Every system you optimize and every process you streamline contributes directly to improving patient outcomes across the globe. 

We are seeking a Manager, Master Data Management, to support our IT Validation team. This role will lead Immatics’ master data strategy during the transition to SAP S/4HANA (go-live: January 1, 2026), overseeing data migration and serving as the long-term governance authority. The Manager will ensure data accuracy, compliance, and consistency across R&D, clinical, and supply chain operations. 

FLSA Classification: Salary, Exempt  
Schedule: 8:00 AM – 5:00 PM; Monday to Friday; On-site  
Reports to: Vice President, IT  
Location: 13203 Murphy Road Suite 100 Stafford, TX 77477  

What You’ll Do: 

As a Manager, Master Data Management , you will play a key role in supporting our IT Validation Operations:  

• Lead the S/4 data‑migration and master data work‑stream (strategy, mapping, cleansing, load & reconciliation). 

• Deploy SAP S/4 HANA to centralize material, supplier, customer and finance master data.  

• Establish and chair the enterprise‑wide master data management. 

• Define data standards, policies and stewardship model aligned to GxP, SOX and other regulations. 

• Orchestrate data preparation, cleansing, load, and validation for each release wave/PI, including mock loads, cutover, and post‑go‑live stabilization with clear Go/No‑Go quality gates. 

• Align cross‑functional stakeholders (Clinical, Manufacturing, Quality, Supply Chain, Finance, Commercial) to deliver on‑time, complete data and close gaps quickly. 

• Monitor KPI‑based data quality, drive continuous improvement and support audits.  

• Hands-on support for validation, testing and maintaining master data. 

• Further develop the master data management landscape in the future e.g. with SAP MDG and other initiatives. 

• Mentor data stewards and champion data literacy across the organization. 

Required Experience and Education: 

• Masters Degree in Computer Science, Engineering, Business Administration, Biology, Chemistry. 

• 3+ years experience in SAP S/4 HANA in a data-related role 

• Knowledge of S/4 data models (Business Partner, Material, Bill-of-Material, Batch, Valuation, Inventory) 

• Influence without authority; professionally relentless in securing inputs and driving decisions to closure across executive, site, and functional stakeholders. 

• Hands‑on with data‑quality rules, profiling, and remediation; comfortable with Excel/ETL concepts to guide teams. 

• Life‑science and GMP experience; understanding of regulatory data requirements like 21 CFR Part 11 and HIPPA. 

Preferred Experience and Education:  

• 8+ years relevant industry experience in consulting or IT/process management. 

• MDG experience is an advantage. 

• Knowledge about industry best practice Enterprise Application Environments including MES, LIMS and eQMS systems. 

• Experience with regulatory requirements based on SOX. 

Competencies:  

• Initiative 

• Problem Solving 

• Proven leadership of multi‑disciplinary teams and external partners.  

• Analytical mindset, excellent communication in English (German a plus). 

Work Environment:  

This is a sedentary position (at least 50% of time) in a typical office environment. There may be frequent interruptions with moderate noise levels and frequent use of printers, copiers, scanners, computers and other office equipment. Ability to sit, talk, walk, hear and communicate verbally and in writing is . Occasional lifting of objects up to 25 lbs is expected.    

Travel required: Based on project assignments or alignments it will be to travel to Germany (Tübingen) 4 times per year. 

Physical demands: 

• Communicating Verbally – expressing or exchanging ideas by means of the spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately, loudly or quickly. 

• Hearing – the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds. 

• Keyboarding – entering data or text into a computer or other machine by means of a keyboard. Devices include a traditional keyboard, 10 key-pad, touch screens and others.  

• Lifting - raising or lowering an object (up to 25 lbs) from one level to another (includes upward pulling). Carrying is to transport an object – usually by holding it in the hands or arms but may occur on the shoulder. 

• Near Visual Acuity – clarity of vision at approximately 20 inches or less (working with small objects, reading small print, including the use of computers).  

• Pushing - Exerting force upon an object so that the object moves away from the object. 

• Pulling - Exerting force upon an object so that the object moves toward the force.  

• Sitting – remaining in a sitting position for at least 50% of the time. 

• Standing/Walking - remain on one's feet in an upright position at a workstation.  

• Stooping – occasional bending the body downward and forward by bending the spine at the waist - requiring full use of the lower extremities and back muscles. 

Work authorization/security clearance requirements:  

Legal eligibility to work in the United States is . Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment.   

Affirmative Action/EEO statement:   

Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs. We do not discriminate on the basis of race, color, religion, national origin, ethnicity, marital status, age, physical or mental disability, medical conditions, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. 

What do we offer?  

 At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics. 

Comprehensive Benefits:  

• Competitive rates for Health, Dental, and Vision Insurance 

• 4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment. 

• Sick Time Off – 56 hours  

• 12 Paid Holidays  

• 100% Employer-Paid Life Insurance up to at 1x annual salary 

• 100% Employer Paid Short- and Long-Term Disability Coverage  

• 401(k) with Immediate Eligibility  & company match… 

• You are eligible for 401(k) plan participation as of your first paycheck. 

• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment. 

• Partially paid Parental Leave for eligible employees. (3 weeks) 

• Additional voluntary employee paid coverages including  Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance.  

Professional Growth:  

• Opportunities to work with leading experts in the field of T-cell immunotherapy.  

• Company provided learning and development opportunities 

• Fast paced, high demand collaborative and dynamic environment.