Scientist, Antibody Discovery & Engineering
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Job Description
ROLE SUMMARY:
As a Scientist, you will be part of Pfizer's Worldwide Research and Development team that employs a multidisciplinary approach to identify cancer targets and develop next generation Oncology therapeutics and therapeutic combinations. In this role, you will contribute to cell engineering and antibody discovery for the development of novel biotherapeutics. You will be responsible for extensive molecular biology, tissue culture and cell biology benchwork, including vector engineering, Polymerase Chain Reaction (PCR), cloning, cell engineering, flow cytometry, and assay development. You will also contribute to molecular analyses of cancer targets, antibody sequencing, identification of sequence liabilities, and antibody engineering.
With your deep knowledge in the discipline, you will be an active team member who influences at the project team level. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience and consulting others. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide your team members. It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.
ADDITIONAL POINTS:
- Contribute to achievement of goals and influence at the project team level
- Provide cell engineering and molecular biology support for multiple Oncology Research projects
- Evaluate data and provide clear reports that can be shared and transferred to and from cross-functional teams
- Pay attention to detail, strictly adhere to safety protocols, and use knowledge of basic laboratory procedures to advance projects under rapidly shifting priorities and timelines
BASIC QUALIFICATIONS:
- Bachelor’s degree + 6 years laboratory research experience or Master’s degree + 4 years laboratory research experience in molecular and cellular biology or related subject
- Proficiency in culturing multiple cell lines under BSL2 conditions
- Substantial experience with at least two cell engineering technologies, such as transfection, nucleofection, lentiviral transduction, and CRISPR
- Experience with multi-color flow cytometry
- Molecular biology skills, including primer design, PCR, and plasmid cloning
- Familiarity with sequence analysis software, such as Snapgene and/or Geneious Prime
- Demonstrated ability to work independently and collaboratively, adapting to project needs
- Ability to organize and prioritize work to meet timelines and deliverables
- Strong written and verbal communication skills, including ability to accurately document experiment data and present results
PREFERRED QUALIFICATIONS:
- Proficiency in quantitative flow cytometry, high throughput flow cytometry, and single-cell sorting
- Understanding of antibody biology and antibody drug conjugates (ADCs)
- NGS library preparation
- Familiarity with Oxford Nanopore sequencing and data analysis
- Experience coding in Python, R, or other programming language
PHYSICAL/MENTAL REQUIREMENTS
- Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis
- Must be able to wear specialized protective clothing and PPE (lab coat, safety shoes/glasses/etc)
Additional Information:
- Relocation support available
- Work Location Assignment: On Premise
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Automate your job search with Sonara.
Submit 10x as many applications with less effort than one manual application.