Associate Director, Project Management (Late Stage/Commercialization)

Position Summary 

The Associate Director (AD), Project Management is responsible for leading complex, high-impact asset programs and enterprise initiatives across the full product lifecycle-from discovery and development through late-stage development, launch readiness, and commercialization. This role ensures alignment with organizational strategy, portfolio priorities, and value creation objectives.

The AD will partner closely with and co-lead strategic planning, scenario analysis, and critical decision-making with the Project Leads (DT/ADT/ACT Leads) and senior functional leaders. Reporting to the Head of Portfolio and Project Management, the AD provides strategic leadership, governance, and executional excellence, ensuring cross-functional teams operate effectively, decisions are data-driven, and programs advance in accordance with the MBX operating model.

This role requires a seasoned leader with strong enterprise mindset, exceptional communication and influencing skills, and the ability to guide cross-functional teams in a fast-paced, evolving environment.

Key Responsibilities

• Lead and oversee MBX's asset and enterprise project plans across development and commercialization, including scope, timelines, milestones, deliverables, resourcing, risks, budgets, key stage-gate and Go/No-Go decisions.
• Drive end-to-end execution of project plans, manage and update cross-functional timelines, proactively identify potential project risks, and develop mitigation and contingency plans with the team to overcome obstacles and ensure project success. 
• Partner closely with Asset Commercialization Leaders for cross-functional commercialization and launch readiness planning, including integration of clinical, regulatory, CMC, supply chain, pricing & market access, medical affairs, sales, and commercial strategy activities.
• Serve as a strategic thought partner to DT/ADT/ACT Leads, supporting long-range planning, prioritization, and trade-off decisions.
• Facilitate decision-making and resolve conflicts efficiently.
• Recommend and adjust plans as needed to ensure timeline progress and goal achievement. 
• Lead and motivate cross-functional teams to achieve project goals.
• Review and provide feedback on program-level strategy related documentation such as regulatory meeting packages.
• Serve as the primary point of contact for all project-related communications and reporting, fostering strong relationships with internal teams and external partners. 
• Prepare and present regular status updates to senior leadership.
• Ensure all project documentation is accurate and up to date.
• Identify strategic or operational challenges that may affect plan execution while collaborating with the team to recognize risks and formulate mitigation strategies.
• Work with the Project Management team to develop, refine, and implement project management methodologies, tools, and best practices to enhance overall project effectiveness.
• Develop and manage, in partnership with Finance, program budgets, forecasts, and long-range financial plans, with a strong focus on cost control, resource optimization, and value creation.
• Provide leadership, training, mentorship, and coaching to junior PMs.
• In addition to asset program/project management, Sr. PMs may support enterprise project management and functional project management if requested.
• Other responsibilities as assigned.

Education & Qualifications 

• Bachelor's degree in relevant scientific discipline required
• 8+ years of experience in the pharmaceutical or biotech industry.
• 8+ years of progressive project management experience managing and leading drug development programs.
• Requires knowledge and understanding of the drug development and commercialization process.
• Demonstrated experience supporting late-stage development, launch readiness, and or commercialization activities.
• Project management and analytical skills, including strong organization, prioritization, multi-tasking, and problem-solving skills. 
• Demonstrated ability to deliver results of high quality, on time, and within budget. 
• Willingness and ability to build and maintain strong, cross-functional relationships within all levels of the department and throughout the organization. 
• Ability to lead and drive results in a cross-functional team environment.
• Project management professional (PMP) certification preferred. 
• Proficiency in the use of project management tools and techniques (e.g., MS Project, MS Excel, MS PowerPoint, etc.). 

Travel

You will be expected to travel periodically based on the needs of the business to the extent requested by the Company including attendance at Together Weeks, Together Days and functional meetings as requested by the Company.

Company Overview:

MBX Biosciences is a biopharmaceutical company focused on the discovery, development and commercialization of novel precision peptide therapies based on its proprietary PEP platform, for the treatment of endocrine and metabolic disorders. The Company is advancing a pipeline of novel candidates for endocrine and metabolic disorders with clinically validated targets, established endpoints for regulatory approval, significant unmet medical needs and large potential market opportunities. The Company's pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism preparing for Phase 3 development; and an obesity portfolio that includes MBX 4291 in Phase 1 development and MBX 5765 in preclinical development, as well as additional discovery candidates. The Company is based in Carmel, Indiana and Burlington, Massachusetts. To learn more, please visit the Company website at www.mbxbio.com and follow it on LinkedIn.

EEO Statement: 

MBX Biosciences is an Equal Opportunity Employer and is committed to treating all applicants fairly without discrimination. We welcome applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law.