Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity:
The Executive Director, Clinical Supply Chain provides strategic leadership and operational oversight for end-to-end clinical supply chain activities across the organization.
Strategic Leadership
Define and execute the global clinical supply chain strategy aligned with the company’s clinical development pipeline and long-term business goals.
Establishes strategies and processes to ensure uninterrupted supply for Revolution Medicines portfolio across all phases of development.
Lead and serve as subject matter expert for clinical supply chain planning, risk management, and execution of clinical supply chain activities.
Build scalable processes and infrastructure to support early- through late-phase clinical programs.
Strategic Planning on comparator sourcing management to ensure timely, compliant and cost-effective product availability.
Effective management of clinical studies executed in conjunction with collaboration partners.
Identify and implement overall clinical supply chain best practices.
Clinical Supply Operations
Oversee end-to-end clinical supply activities, including demand forecasting, protocol reviews, packaging, labeling, distribution, and returns.
Ensure uninterrupted supply of investigational medicinal products (IMP), including RevMed and comparator products.
Champions monthly Development Operations planning (DnOP) process in collaboration with PDM and Clinical Operation team members.
Ensures efficient global clinical supply chain distribution networks are in place.
Oversee comparator products demand and supply planning with expert level knowledge in comparator drugs and co-medications sourcing strategy
Cross-Functional Collaboration
Partner with Clinical Operations and Clinical Study Execution Teams (CSET) in study planning and execution.
Collaborate with PDM, Quality, and Regulatory to ensure compliant manufacturing, labeling, and distribution
Work closely with Finance on budgeting, forecasting, and cost optimization.
Work effectively with internal and external partners to develop sound strategies, identify and mitigate risks, and resolve issues as they arise.
Compliance & Quality
Ensure all clinical supply activities comply with GxP, ICH, FDA, EMA, and global regulatory requirements.
Expert knowledge of applicable GxP requirements and applicable regulatory guidances.
Lead inspection readiness activities as required for global filings and maintain and inspection ready organization.
Team Leadership
Build, lead, and mentor a high-performing clinical supply chain organization. Drives for excellence in execution of agreed upon strategies.
Establish clear performance metrics, development plans, and succession planning.
Foster a culture of accountability, continuous improvement, and collaboration.
Drives excellence in setting clear and actionable team goals.
Required Skills, Experience and Education:
Bachelor’s degree in Supply Chain, Business, Engineering or Life Sciences with 20+ years of experience in pharmaceutical supply chain. Master’s degree (MS, MBA) with at least 18 years of experience in pharmaceutical/biotech supply chain.
CPIM/CSCP certifications a plus.
At least 5 years of experience in a leadership/supervisory role.
Strong knowledge and experience with cGMP operations for small molecules, end- to end supply chain and demand/supply planning.
Effective vendor management and oversight skills
Excellent cross-functional leadership skills with effective communication skills.
Preferred Skills:
Proven leadership experience hiring, managing and developing teams.
Knowledge and experience with outsourced manufacturing operations. (CMO’s)
Effective, open and transparent communication skills (verbal and written). Strong analytical, communication and executive level reporting skills.
Capable of working on multiple projects/tasks and able to meet timelines.
Self-starter with a high-level of comfort with ambiguity and complexity and the ability to multi-task while consistently delivering quality results.
Team-oriented, progressive thinker who enjoys participating in an innovative and creative work environment.
#LI-Hybrid #LI-GL1
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.
Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
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We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.