Postdoctoral Associate - Droujinine Lab - Molecular & Cellular Biology

ABOUT US:

Scripps Research is a nonprofit biomedical institute ranked as one of the most influential in the world for its impact on innovation. We celebrated our 100-year legacy in 2024. This significant milestone marks a century of seminal discoveries in immunology, infectious diseases (such as COVID-19, flu, HIV), neuroscience, heart disease, cancer, and more. Located in La Jolla, California, the institute houses six research departments, multiple Nobel laureates, a top-ranked graduate school and a leading postdoctoral training program. Scripps Research encompasses two elite and highly innovative institutes, the Calibr-Skaggs Institute for Innovative Medicines and Scripps Research Translational Institute, which merge foundational studies in biology, chemistry and computer science with translational science to produce pioneering drugs and advances in digital and precision medicine. Together, we cultivate new scientific leaders and expand the frontiers of knowledge to deliver medical breakthroughs impacting human health around the globe. If you have a passion for making a difference, this could be your opportunity to join our transformative team.

POSITION TITLE: Postdoctoral Associate

POSITION SUMMARY:

We are seeking a highly motivated Postdoctoral Associate. Ideal candidate will lead their own project, and perform mammalian cell culture, in vivo mouse experiments, in vivo genetic screens, quantitative TMT mass spectrometry proteomics, metabolomics, western blot, pulldowns, DNA cloning, immunostaining, confocal microscopy, high throughput screens, and bioinformatic data analysis. Significant emphasis is placed on the professional development of the Postdoctoral Associate. More information on the project will be discussed during the interview process.

Lab Project Overview: To maintain homeostasis, organisms rely on internal signaling networks that orchestrate the physiological response across different tissues and organs. Intriguingly, perturbation in one tissue elicits secreted signals that transmit the information to other tissues and that these signals are important for maintenance of health and longevity. Secreted proteins are key components of interorgan signaling that coordinate organ functions by signaling over long distances. Destabilization of these interorgan signaling networks, responsible for the orchestration of physiological responses across organs, drives age-associated disease, including diabetes, cancer, or chronic inflammation. Despite this, the composition and activity of interorgan communication networks and their impact on aging and disease remain poorly defined. The Droujinine Lab has developed novel methods to identify and characterize novel secreted factors that coordinate organ functions in homeostasis and disease in mammalian systems. Specifically, we use proteomics and in vivo functional genomic screens to uncover the secreted proteins and cellular circuitry involved in homeostasis, obesity, and aging. To learn more please visit www.scripps.edu/droujinine

Contact: idroujinine@scripps.edu

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REQUIREMENTS:

• PhD degree in biology, physiology, neuroscience, chemical biology, biological engineering, or related discipline. Candidates who are about to defend their thesis are welcome to apply.
• Experience in biologic techniques outlined in the position summary highly preferred but not required
• High motivation and independence in reading scientific literature and performing experiments

PHYSICAL REQUIREMENTS:

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

COMPENSATION: Postdoctoral Associates will be hired following the National Institute of Health and California's exempt salary guidelines, which provide for a starting range of $70,304- $75,353. Consideration will be given to experience that exceeds the listed requirements.

COMPREHENSIVE BENEFITS INCLUDE:

• Eligibility for retirement plans with employer contribution.
• Full suite of Health and Welfare plans including four medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more.
• Access to Dependent Flexible Spending Accounts.
• Paid Time Off - 5 days annually
• Free, on-site Counseling Center which provides confidential counseling services to benefits-eligible employees.
• Free, on-site parking.
• Pet Insurance

The above statements describe the level of work performed and expected in general terms. The statements are not intended to list all the responsibilities, duties and/or skills required of employees so classified, and the content herein is subject to change due to the business needs of Scripps Research, with or without notice. Furthermore, nothing in this job description shall be interpreted to be in conflict with or to eliminate or modify in any way the employment-at-will status of Scripps Research staff.

EEO Statement: Scripps is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.