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Head of Research Operations

Mosaic BiosciencesBoulder, CO

$170,000 - $215,000 / year


Overview

Schedule
Full-time
Career level
Executive
Remote
On-site
Compensation
$170,000-$215,000/year
Benefits
Career Development

Job Description

Mosaic is seeking an experienced scientific and operational leader to lead our multidisciplinary Research organization. The Head of Research Operations will provide operational oversight to ensure scientific excellence, effective execution, and timely delivery of high-quality, partner-aligned outcomes in a dynamic CRO environment. This role will lead and support our functional leaders across Research, aligning teams, resources, and priorities with our partners’ goals and objectives. Success requires a proactive, customer-first mindset, strong scientific judgment, a sense of urgency, and an appreciation for the pace and operational demands of a CRO setting.Primary ResponsibilitiesOperational Leadership
  • Provide operational oversight to ensure research capabilities remain cutting-edge, efficient, and aligned with current and future partner needs.
  • Translate partner goals and program needs into actionable operational plans with defined deliverables, timelines, and resource allocation.
  • Oversee the execution and troubleshooting of multidisciplinary discovery projects, maintaining scientific rigor, efficiency, and cross-team alignment.
  • Foster a culture of continuous improvement and innovation by implementing best practices, integrating new technologies (e.g., automation, high-throughput systems, data analytics), and staying current with trends in biologics discovery.
  • Collaborate with executive leadership to develop and implement long-term research strategies, identifying and evaluating emerging industry trends for internal investment and potential acquisitions.
Team Leadership and Development
  • Empower functional leadership to drive accountability, scale execution, and consistently delivery across the Research organization.
  • Lead, mentor, and inspire a multidisciplinary team of scientists to achieve high performance and deliver exceptional results to partners.
  • Build and nurture a collaborative, inclusive environment that encourages problem-solving, gathering alternative views and opinions, and knowledge sharing across disciplines.
  • Set clear goals, expectations, and performance metrics; provide ongoing feedback and coaching to support professional growth and team success.
  • Cultivate a culture that prioritizes accountability, responsiveness, and excellence in partner service – hallmarks of successful CRO operations.
  • Ensure teams remain scientifically current and technically innovative in ways that directly support customer goals and differentiate Mosaic’s service offerings.
Cross-Functional Collaboration and Communication
  • Collaborate with Commercial leadership on strategic client discussions and proposals, ensuring technical commitments align with partner needs, Mosaic capabilities, and business priorities.
  • Communicate effectively with internal and external stakeholders to provide transparent updates on project status, scientific progress, and strategic initiatives.
  • Collaborate with the Commercial team to understand client needs and ensure technical teams are aligned with business priorities and scientific expectations.
  • Represent Mosaic as a scientific leader at conferences, business meetings, and industry forums to enhance the company’s visibility and reputation.
Qualifications:
  • PhD or equivalent in a relevant life sciences field (e.g., Biochemistry, Immunology, Molecular or Cell Biology).
  • 10+ years of experience in biologics discovery, with at least 5 in operational or scientific leadership roles.
  • Proven track record of managing multi-functional teams in fast-paced biotech, pharma, or CRO environment – ideally with direct experience supporting external client programs.
  • Demonstrated ability to respond with urgency and clarity to evolving partner priorities, scope changes, or new technical challenges.
  • Deep understanding of discovery workflows, particularly across protein and antibody engineering.
  • Strong communication skills, with experience leading technical teams and external-facing relationships.
  • Demonstrated ability to thrive in a CRO or service-oriented environment, balancing scientific excellence with time- and cost-sensitive deliverables.
  • Strong appreciation for client service dynamics, including proactive communication, expectation management, and responsiveness to shifting program needs.
Location: On-site – 5710 Flatiron Parkway, Boulder, CO 80301Department: Research & DevelopmentLevel: Sr. DirectorCompensation: $170,000 - $215,000

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FAQs About Head of Research Operations Jobs at Mosaic Biosciences

What is the work location for this position at Mosaic Biosciences?
This job at Mosaic Biosciences is located in Boulder, CO, according to the details provided by the employer. Some roles may also include multiple work locations depending on the requirement.
What pay range can candidates expect for this role at Mosaic Biosciences?
Candidates can expect a pay range of $170,000 and $215,000 per year.
What employment applies to this position at Mosaic Biosciences?
Mosaic Biosciences lists this role as a Full-time position.
What experience level is required for this role at Mosaic Biosciences?
Mosaic Biosciences is looking for a candidate with "Executive" experience level.
What benefits are offered by Mosaic Biosciences for this role?
Mosaic Biosciences offers Career Development for this position. Actual benefits may vary depending on the employer's policies and employment terms.
What is the process to apply for this position at Mosaic Biosciences?
You can apply for this role at Mosaic Biosciences either through Sonara's automated application system, which helps you submit applications 10X faster with minimal effort, or by applying manually using the direct link on the job page.