Laboratory Sciences Professional (Open Rank)

University of Colorado Anschutz

Department: Pediatrics, Section of Developmental Biology

Official Title: Laboratory Sciences Professional (Open Rank)

Position #: 00811014 - Requisition #: 39231

Job Summary:

The Zhu Laboratory at the University of Colorado Anschutz Medical Campus is seeking a highly motivated Research Services Professional to join a dynamic team focused on stem cell biology, regenerative medicine, and diabetes research. Our lab investigates how human pluripotent stem cells differentiate into pancreatic β-cells and applies cutting-edge tools-including CRISPR-based engineering, genomics, artificial intelligence-guided regulatory design, and functional metabolic assays-to develop next-generation cell therapies for type 1 diabetes.

This position offers the opportunity to contribute directly to high-impact translational research. The selected candidate will perform molecular and cellular experiments, support stem cell differentiation workflows, and assist in developing and optimizing functional assays that evaluate β-cell identity and performance. At the senior level, this role includes independent experimental planning, assay development, and active participation in data interpretation and research advancement.

Key Responsibilities:

• Perform basic molecular biology techniques, including buffer preparation, sample collection, RNA/DNA extraction, PCR, real-time qPCR, cloning, bacterial culture, mini-prep, sequencing, sample submission, gel electrophoresis, Western blotting, immunofluorescence staining, and fluorescence microscopy.

• Maintain laboratory organization, including receiving and logging reagents/products, tracking inventory, autoclaving materials, managing biological waste, and general laboratory upkeep.

• At the Senior level, perform mammalian cell culture, static and dynamic glucose-stimulated insulin secretion assays, luciferase/reporter assays, lentiviral production and transduction, and flow cytometry analysis after training.

• Accurately document experiments, organize data, and communicate results to the PI and lab team.

• Assist with laboratory protocols, SOP updates, and ordering supplies.

• Comply with all institutional guidelines for biosafety, chemical safety, and research integrity.

Work Location:

Onsite - this role is expected to work onsite and is located in Aurora, CO.

Why Join Us:

Are you passionate about cutting-edge science and motivated to make a real-world impact on human health? Join the Zhu Lab at the University of Colorado Anschutz Medical Campus, where we are pushing the boundaries of stem cell biology and regenerative medicine to develop transformative therapies for type 1 diabetes.

Our team investigates how human pluripotent stem cells become pancreatic β-cells and engineers next-generation stem cell-derived islets with improved precision, stability, and therapeutic potential. We integrate molecular biology, genomics, CRISPR-based genome engineering, artificial intelligence-guided regulatory design, and functional metabolic assays to answer fundamental questions in development while accelerating translation toward clinical application. As part of our team, you will gain hands-on experience with advanced technologies in a high-impact, fast-paced research environment. You will contribute directly to projects aimed at improving β-cell specification and developing innovative strategies for diabetes therapy. This role offers meaningful opportunities for technical growth, scientific development, and active participation in research with direct translational relevance.

The University of Colorado Anschutz Medical Campus provides a vibrant, interdisciplinary scientific community with state-of-the-art research facilities and strong collaborations across basic science and clinical departments. Here, your

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation, and sick leave! The University of Colorado offers an excellent benefits package, including:

• Medical: Multiple plan options

• Dental: Multiple plan options

• Additional Insurance: Disability, Life, Vision

• Retirement 401(a) Plan: Employer contributes 10% of your gross pay

• Paid Time Off: Accruals over the year

• Vacation Days: 22/year (maximum accrual 352 hours)

• Sick Days: 15/year (unlimited maximum accrual)

• Holiday Days: 15/year

• Tuition Benefit: Employees have access to this benefit on all CU campuses

• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Qualifications:

Minimum Qualifications:

Intermediate Level:

• Bachelor's degree in biology, molecular biology, cell biology, biochemistry, genetics, bioengineering, or a related field.

• One (1) year of experience in an experimental or wet laboratory.

Senior Level:

• Bachelor's degree in biology, molecular biology, cell biology, biochemistry, genetics, bioengineering, or a related field.

• Two (2) years of experience in an experimental or wet laboratory.

Substitution (All Levels): A combination of education and related technical/military/paraprofessional experience may be substituted for a bachelor's degree on a year-for-year basis.

Applicants must meet minimum qualifications at the time of hire.

Applicants must be legally authorized to work in the United States without requiring sponsorship. We are unable to provide work visa sponsorship or employment authorization for this position now or in the future.

Preferred Qualifications (All Levels):

• Experience with mammalian cell culture, including maintenance, passaging, and basic functional assays.

• Hands-on experience with CRISPR-based workflows, such as plasmid preparation, cloning, or genotyping validation.

• Experience performing flow cytometry sample preparation, acquisition, or analysis.

• At least one (1) year of full-time laboratory research experience in molecular biology, stem cell biology, developmental biology, or a related field beyond coursework.

Conditions of Employment (All Levels):

• Must be willing and able to pass a national criminal background check.

• For questions regarding Children's Hospital drug testing requirements, please contact Children's Human Resources at 720-777-8598. Some positions may require testing if access to Children's Hospital or their systems is needed at any time during employment with the University. If drug testing is required, it will be listed in the job posting.

Knowledge, Skills, and Abilities:

Intermediate Level:

• Ability to follow established laboratory protocols with accuracy and attention to detail.

• Ability to learn new laboratory techniques and incorporate feedback into daily work.

• Ability to maintain clear, organized experimental records and document results consistently.

• Ability to manage time effectively and complete assigned tasks with minimal supervision.

• Ability to work cooperatively within a research team and contribute to shared responsibilities.

Senior Level:

• Ability to independently plan, execute, and troubleshoot laboratory procedures.

• Ability to adapt to evolving project needs and implement new technical approaches.

• Ability to organize, prioritize, and coordinate multiple experiments simultaneously.

• Ability to document and interpret experimental results with a high level of accuracy.

• Ability to assist in guiding junior lab members and support a collaborative research environment.

How to Apply:

For full consideration, please submit the following document(s):

• A letter of interest describing relevant job experiences as they relate to the listed job qualifications and interest in the position

• Curriculum vitae / Resume

• Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Questions should be directed to: Han Zhu, Han.Zhu@cuanschutz.edu

Screening of Applications Begins:

Immediately and continues until the position is filled. For best consideration, apply by April 6, 2026.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as:

• Intermediate Level: $50,357 to $64,054

• Senior Level: $54,440 to $69,248

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans, and retirement contributions that add to your bottom line.

Total Compensation Calculator

Equal Employment Opportunity Statement:

CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students, and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine-preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety-sensitive job duties, you must enroll in the occupational health medical surveillance program.