Manager, Supply Planning
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Overview
Job Description
Manager, Supply Planning Location: Boston MA Duration: 12 Months Pay: $ 84.54- $99.46 POSITION SUMMARY The Manager, Supply Planning is embedded within Client's External Manufacturing organization. This individual will own the end-to-end supply planning function for Verve Therapeutics' clinical programs, operating in a fully outsourced CDMO model built on mRNA/LNP technology. The role is foundational to the team's S&OP process design and will serve as the primary driver of 18-month rolling MRP for clinical drug product supply. KEY RESPONSIBILITIES Supply Planning & MRP Develop and maintain rolling supply plans for clinical drug product Generate forward-looking material requirements for drug substance intermediates and critical excipients Manage supply plan assumptions, risk scenarios, and inventory coverage targets in alignment with program timelines S&OP Process Development Build and maintain S&OP templates, KPIs, and reporting dashboards Prepare and present supply plan summaries for cross-functional leadership reviews CDMO Network Coordination Translate supply plans into manufacturing schedules coordinated across external CDMOs Monitor schedule adherence, batch release timelines, and supply risk through collaborative CDMO governance Maintain material genealogy and lot traceability across the multi-step supply chain Risk & Inventory Management Develop safety stock strategies for critical materials, accounting for CDMO lead times, shelf-life/expiry constraints, and clinical trial uncertainty Identify and escalate supply risks with mitigation options framed for leadership decision-making Support annual reportable change and regulatory change management (CMC) from a supply continuity standpoint QUALIFICATIONS Required Bachelor's degree in Supply Chain, Engineering, Life Sciences, or related field; advanced degree a plus 5+ years of supply chain or supply planning experience in pharmaceutical, biotech, or CDMO environment Hands-on experience with MRP/ERP systems (SAP strongly preferred) Direct experience with clinical supply planning in an outsourced manufacturing model Strong analytical skills; proficiency with supply planning tools and Excel/dashboard platforms Preferred Experience with advanced therapy or biologic modalities (LNP, mRNA, gene therapy, oligonucleo
Product) Familiarity with S&OP/IBP process design and implementation Exposure to CMC regulatory requirements (IND-stage) and supply risk classification APICS CPIM or CSCP certification
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