Post Doctoral Fellow

Who is Saint Louis University? Founded in 1818, Saint Louis University is one of the nation's oldest and most prestigious Catholic universities. SLU, which also has a campus in Madrid, Spain, is recognized for world-class academics, life-changing research, compassionate health care, and a strong commitment to faith and service.

We proudly celebrate 100 years since the founding of the department in 1924 by Dr. Edward A. Doisy, recipient of the 1943 Nobel Prize in Physiology or Medicine for his work on the synthesis of vitamin K.

The tradition of excellence started by Dr. Doisy continued with the remarkable scientific achievements of his successors, Dr. Robert Olson and Dr. William Sly.

Today, faculty in BMB honor this tradition with work at the forefront of disciplines like blood coagulation, DNA repair, and lipid metabolism, supported by state-of-the-art facilities and instrumentation. A generous endowment bestowed by Dr. Doisy on BMB is being used to grow and support our innovative and transformative biomedical research.

It is an exciting time to join us in BMB as a postdoc.

The research associate (postdoctoral fellow) will work closely with a large research team (including SLU Education Policy faculty and graduate students, researchers in the SLU PRiME education policy research center, and SLPS administrative staff) to conduct research on Missouri education data, SLPS data, and continue their own research agenda. The ideal candidate will have experience conducting program evaluations and designing research projects related to education policy issues.

NIH funded postdoctoral positions are available to study the structural enzymology of proteins responsible for blood coagulation (https://biochem.slu.edu/faculty/dicerawp/) with the goal of unraveling the molecular architecture and mechanism of the underlying interactions. The approach uses a combination of conventional (rapid kinetics, protein engineering, X-ray crystallography) and innovative (smFRET, cryo-EM) biophysical techniques. Current projects in the lab focus on the interaction of prothrombin with prothrombinase, leading to generation of thrombin and blood clotting, the activation of factor V required for assembly of prothrombinase and the interaction of the thrombin-thrombomodulin complex with protein C that halts the coagulation response. Additional studies focus on factor V short and its interactions with TFPIalpha, protein S and factor Xa and on proteins of the contact pathway like factors IX, XI and XII.

Function

Medical Research Primary Appointment 12 mo.

Scheduled Weekly Hours:

40

Saint Louis University is an equal opportunity/affirmative action employer. All qualified candidates will receive consideration for the position applied for without regard to race, color, religion, sex, age, national origin, disability, marital status, sexual orientation, military/veteran status, gender identity, or other non-merit factors. If accommodations are needed for completing the application and/or with the interviewing process, please contact Human Resources at 314-977-5847.