Postdoctoral Research Associate - Chemical Biology & Therapeutics

St. Jude Children's Research HospitalMemphis, Tennessee

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Overview

Schedule

Full-time

Education

Doctorate Degree

Career level

Senior-level

Remote

On-site

Job Description

A postdoc position is available immediately in the laboratory of Dr. Daniel Blair which focuses on leveraging high-throughput chemical synthesis and MS/MS analysis to create predictive models of chemical reactivity.

Substrate aware reaction condition prediction

This project seeks to capitalize on our recent development of rapid tandem mass-spectrometry methods to scout chemical reaction outcomes (Nature2024, JACS2026, Nature Protocols 2026). The proposed data rich experimentation will connect chemical structures to optimal reaction conditions. A competitive candidate will have a background in synthetic organic chemistry, experience with either automated synthesis or high-throughput experimentation is desirable. The project will be executed in the Department of Chemical Biology and Therapeutics at St. Jude Children’s Research Hospital and builds on strong investments into a world-class infrastructure in high-throughput chemical synthesis and analysis.

Please direct queries and application packets including a cover letter, current CV, and contact information for 3 referees to Dr. Daniel Blair (daniel.blair@stjude.org).

Papers/Links:

U Neelakantan, … D J Blair * Generalized Analysis of Electrophilic Small Molecules, ChemRxiv2026 doi: 10.26434/chemrxiv.10001482/v1

M Hu*, D J Blair * High-throughput reaction screening using acoustic ejection mass spectrometry, Nature Protocols2026 doi: 10.1038/s41596-025-01320-y

M Hu, … D J Blair * Direct-to-Biology Enabled Molecular Glue Discovery JACS2026

doi: 10.26434/chemrxiv-2025-4d7nq

M Hu… D J Blair * Continuous Collective Analysis of Chemical Reactions Nature2024

doi: 10.1038/s41586-024-08211-4

https://www.science.org/content/blog-post/real-high-throughput-chemistry-through-mass-spec

Minimum Experience

PhD in Organic Chemistry

St. Jude is an Equal Opportunity Employer

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FAQs About Postdoctoral Research Associate - Chemical Biology & Therapeutics Jobs at St. Jude Children's Research Hospital

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This job at St. Jude Children's Research Hospital is located in Memphis, Tennessee, according to the details provided by the employer. Some roles may also include multiple work locations depending on the requirement.

What pay range can candidates expect for this role at St. Jude Children's Research Hospital?

Employer has not shared pay details for this role.

What employment applies to this position at St. Jude Children's Research Hospital?

St. Jude Children's Research Hospital lists this role as a Full-time position.

What experience level is required for this role at St. Jude Children's Research Hospital?

St. Jude Children's Research Hospital is looking for a candidate with "Senior-level" experience level.

What education level is required for this job?

The education requirement for this position is Doctorate Degree. Candidates with relevant qualifications or equivalent experience may also be considered.

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