Raii - Sra, Analytical Development
Chroma MedicineBoston, MA
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Overview
Schedule
Full-time
Education
Engineering (PE)
Career level
Senior-level
Remote
On-site
Benefits
Career Development
Job Description
ABOUT THE ROLE
The Analytical Development team is seeking a motivated and detail-oriented Research Associate to support advancement of the company's LNP platform and ongoing clinical programs. The successful candidate will work closely with senior team members to support LNP process development, execute analytical testing for in vivo studies, and contribute to the characterization of LNPs as well as mRNA and gRNA payloads.
RESPONSIBILITIES
- Contribute to development of suitable biochemical and biophysical tools for characterizing LNPs containing RNA payloads used in epigenetic editing applications
- Optimize and troubleshoot existing analytical methods to improve accuracy, reliability, and sensitivity
- Collaborate with research and process development groups to routinely characterize products and process intermediates
- Contribute to design of experiments, analyze data, and document laboratory work in electronic lab notebooks
- Contribute ideas and present scientific findings at team meetings
- Assist with troubleshooting and regular maintenance of critical laboratory equipment and ordering of reagents and consumables
SKILLS & COMPETENCIES:
- Hands-on experience with biophysical characterization of lipid nanoparticle formulations (e.g., SEC-MALS, AF4-MALS, DSC, cIEF, NTA, DLS, SAXS) and/or analysis and characterization of therapeutic nucleic acids (mRNA, oligonucleotides, plasmids) by chromatography (e.g., IPRP/IEX HPLC) and electrophoresis (e.g., CGE) required
- Experience with molecular and immunoassays (e.g., PCR, ELISA) is a plus
- Experience troubleshooting and optimizing routine analytical methods and experimental workflows, including instrumentation
- Working knowledge of data analysis and basic statistical approaches (e.g., quantification, trending)
- Strong organizational skills and attention to detail, with ability to manage multiple priorities in a fast-paced environment
- Strong communication skills and ability to work collaboratively within cross-functional teams
- Demonstrated curiosity and willingness to learn new techniques and support evolving project needs
QUALIFICATIONS:
- Bachelor's or Master's degree in Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical or Biomedical Engineering, or a related field, with 4-6 years (BS) or 2-4 years (MS) of relevant industry experience in the biopharmaceutical industry
- Demonstrated experience executing experiments independently in a fast-paced industry setting
- Familiarity with electronic lab notebooks (e.g., Benchling) highly desired
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FAQs About Raii - Sra, Analytical Development Jobs at Chroma Medicine
What is the work location for this position at Chroma Medicine?
This job at Chroma Medicine is located in Boston, MA, according to the details provided by the employer. Some roles may also include multiple work locations depending on the requirement.
What pay range can candidates expect for this role at Chroma Medicine?
Employer has not shared pay details for this role.
What employment applies to this position at Chroma Medicine?
Chroma Medicine lists this role as a Full-time position.
What experience level is required for this role at Chroma Medicine?
Chroma Medicine is looking for a candidate with "Senior-level" experience level.
What education level is required for this job?
The education requirement for this position is Engineering (PE). Candidates with relevant qualifications or equivalent experience may also be considered.
What benefits are offered by Chroma Medicine for this role?
Chroma Medicine offers Career Development for this position. Actual benefits may vary depending on the employer's policies and employment terms.
What is the process to apply for this position at Chroma Medicine?
You can apply for this role at Chroma Medicine either through Sonara's automated application system, which helps you submit applications 10X faster with minimal effort, or by applying manually using the direct link on the job page.