Research Associate, Preclinical Development

Research Associate / Sr. Research Associate, Preclinical/Product Development

About Krystal Bio: At Krystal Biotech, we bring together the brightest and most eager minds to relentlessly pursue the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs.

Founded in 2016, Krystal is distinguished in three powerful ways: science and technology using our patented gene therapy platform, innovative manufacturing supported by our commercial scale facilities, and a unique commercialization model that focuses on the patient's end-to-end experience.

Krystal received U.S. FDA approval for the first and only redosable gene therapy treatment, VYJUVEK, for the treatment of Dystrophic Epidermolysis Bullosa (DEB). Krystal continues to leverage our proprietary platform to rapidly advance a robust pipeline of investigational genetic medicines in respiratory, oncology, dermatology, and ophthalmology.

Krystal is headquartered in Pittsburgh, PA, which is home to our two state-of-the-art CGMP manufacturing facilities with teams around the world and satellite offices in Switzerland, Germany, and Japan. We are a company built and run by people who care, are fearless in the face of a challenge, love the work they do, and practice the highest level of scientific integrity. As we grow, we are seeking team members that embody these values.

Job Description Summary:

The Product Development Team is seeking a highly motivated and innovative Research Associate / Senior Research Associate to join our multidisciplinary R&D team. The candidate will provide technical and scientific support in the development and testing of HSV-based gene therapy products and will participate in the design, development, and execution of experiments. To be successful, the candidate should demonstrate proficiency in fundamental molecular biology techniques and mammalian cell culture, show curiosity, initiative, and the ability to work well in a timeline-driven environment.

Primary Responsibilities:

• Design and execute studies to address fundamental question about our HSV-based gene therapy product candidates
• Adhere to scientifically-sound practices for experiment documentation, statistically driven data analysis, and interpretation of results
• Ensure that all safety guidelines are always followed strictly and maintain a clean and orderly environment
• Read the literature, find creative opportunities, and suggest alternative approaches to troubleshoot technical issues and plan next steps to meet deliverables.
• Write documents such as standard operating procedures, technical memos, and reports
• Interact with cross-functional teams and effectively communicate scientific results
• Other duties as assigned

Requirements and Desired Competencies:

• Bachelor's Degree (or Master's Degree) in life sciences with relevant laboratory experience
• Industry experience a plus
• Demonstrated experience with cloning, qPCR, aseptic cell culture techniques, virus production, ELISA, Western Blotting, and Immunostaining. Histology experience preferred (paraffin embedding, sectioning, staining).
• Hands-on experience working with rodent models a plus
• In depth understanding in one or more of the following areas is required: gene therapy, cell biology, molecular biology, immunology, and/or virology
• Experience with analytical method development and/or validation a plus
• High capability of multitasking in a fast-paced environment
• Excellent oral and written communication skills

Krystal Biotech, Inc. is an Equal Employment Opportunity and Affirmative Action Employers. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, or disability status. Headhunters and recruitment agencies may not submit resumes/CVs through this Web site or directly to managers. Krystal Biotech, Inc. does not accept unsolicited headhunter and agency resumes. Krystal Biotech, Inc. will not pay fees to any third-party agency or company that does not have a signed agreement with Krystal Biotech, Inc.