Research Associate I/II – Clinical Pathology/IHC Biomarker Development
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Overview
Schedule
Full-time
Career level
Senior-level
Compensation
$60,000-$80,000/year
Benefits
Health Insurance
Dental Insurance
Vision Insurance
Job Description
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.We are seeking a highly organized and detail-oriented Research Associate I/II to support the development, optimization, and validation of immunohistochemistry (IHC) assays. This role will contribute to early-stage biomarker in support of clinical trial programs.The ideal candidate will have 2–3 years of hands-on industry experience in histology, IHC, or a regulated laboratory environment (e.g., CLIA/CAP, GLP). This is a bench-focused position requiring close collaboration with scientists, pathologists, and cross-functional project teams.Key ResponsibilitiesHistology
- Perform tissue sectioning of FFPE blocks.
- Route and support H&E staining workflows.
- Perform routine IHC staining on FFPE tissue specimens using automated platforms (e.g., Ventana, Leica).
- Conduct antibody titrations, protocol optimization, slide preparation, and quality control checks.
- Assist in generating feasibility, optimization, and analytical validation data for emerging CDx assays.
- Experience with Akoya PhenoImager HT platforms is preferred.
- Manage tissue samples and associated documentation.
- Prepare tissue sections, including slide cutting, baking, antigen retrieval, and reagent preparation.
- Maintain sample integrity, traceability, and documentation in compliance with quality system requirements.
- Support tissue handling workflows (blocks, slides, labeling, storage) within GLP or CLIA/CAP environments.
- Accurately record experimental data in ELN and/or LIMS systems.
- Capture high-quality slide images and perform basic image analysis.
- Assist with slide scoring preparation and data summaries.
- Summarize experimental findings for internal meetings and assay development reviews.
- Operate, calibrate, and troubleshoot automated IHC staining platforms and related laboratory equipment.
- Perform routine instrument maintenance and maintain equipment logs per laboratory quality systems.
- Monitor and manage inventory of reagents, antibodies, controls, and consumables.
- Collaborate with scientists, pathologists, QA, and clinical development teams on assay transfer, optimization, and validation activities.
- Support preparation of study materials, controlled documents, and protocol execution for validation studies.
QualificationsRequired
Compensation and Benefits:The expected base salary range for this position is $60,000 - $80,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.- BS or MS in Biology, Molecular Biology, Pathology, Biomedical Sciences, or a related field.
- 1–3 years of hands-on experience in histology and/or IHC assay execution within a research or regulated diagnostic laboratory.
- Experience handling FFPE tissues and operating automated IHC staining platforms.
- Strong attention to detail with excellent documentation and record-keeping practices.
- Ability to follow SOPs and work effectively in CLIA-, GxP-, or ISO-regulated environments.
- Experience supporting IHC assay optimization and/or analytical validation studies.
- Exposure to Akoya platforms and multiplex immunofluorescence projects.
- Experience with digital pathology, slide scanning, or image analysis tools.
- Knowledge of antibody characterization and tissue-based biomarker assay development.
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FAQs About Research Associate I/II – Clinical Pathology/IHC Biomarker Development Jobs at Systimmune
What is the work location for this position at Systimmune?
This job at Systimmune is located in Redmond, WA, according to the details provided by the employer. Some roles may also include multiple work locations depending on the requirement.
What pay range can candidates expect for this role at Systimmune?
Candidates can expect a pay range of $60,000 and $80,000 per year.
What employment applies to this position at Systimmune?
Systimmune lists this role as a Full-time position.
What experience level is required for this role at Systimmune?
Systimmune is looking for a candidate with "Senior-level" experience level.
What is the process to apply for this position at Systimmune?
You can apply for this role at Systimmune either through Sonara's automated application system, which helps you submit applications 10X faster with minimal effort, or by applying manually using the direct link on the job page.