
Research Associate/Senior Research Associate, Protein Engineering
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Overview
Schedule
Full-time
Career level
Entry-level
Remote
On-site
Compensation
$60,000-$85,000/year
Benefits
Health Insurance
Dental Insurance
Vision Insurance
Job Description
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.We are seeking a skilled Research Associate/Senior Research Associate with experience in utilizing display technologies (yeast/phage) in protein engineering, directed evolution, or binder discovery. This is a laboratory-based role that will be supporting protein engineering efforts in discovering novel binders and novel protein leads/scaffolds. The position will join a growing protein engineering team in an innovative organization and reports to the Director of Protein Engineering. The ideal candidate will be a quick learner with a broad experience set with direct expertise in a display technology and/or an adjacent field including but not limited to high throughput molecular biology, antibody/binder discovery, and protein engineering.Industry experience in biologics drug development is required. Key Responsibilities:
- Design and generate display libraries with guidance from experimental and computational data. This includes library preparation and QC, NGS sequencing, and flow cytometry-based lead selection.
- Culture engineered yeast for use in lead selection and sorting.
- Construct/convert immune-based repertoires from immunized animal sources for use in both discovery and protein engineering campaigns.
- Troubleshoot technical issues and implement solutions to optimize lead molecules, ensuring data quality and integrity throughout the discovery and optimization process.
- BS or MS in immunology, biochemistry, molecular biology, structural biology, or a related field. Title and compensation commensurate with experience
- 1+ year industrial drug development experience
- 1+ years of hands-on experience in an aspect of display campaigns or genomics approaches in protein design or directed evolution projects
- Demonstrated proficiency in one or more of the following workstreams: library design and generation, display-based selection, and assay development
- Strong molecular biology background and experience. Library generation experience is a plus
- Cell culture experience (bacterial, mammalian, and/or yeast) is required
- Experience in FACS-based selection and sorting preferred
- Excellent problem-solving skills, with the ability to troubleshoot technical issues and implement effective solutions
- Outstanding organizational skills, attention to detail, and the ability to manage multiple projects simultaneously in a fast-paced environment
- Strong communication and interpersonal skills, with the ability to collaborate effectively within multidisciplinary teams
- On-site work is mandatory
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FAQs About Research Associate/Senior Research Associate, Protein Engineering Jobs at Systimmune
What is the work location for this position at Systimmune?
This job at Systimmune is located in Redmond, Washington, according to the details provided by the employer. Some roles may also include multiple work locations depending on the requirement.
What pay range can candidates expect for this role at Systimmune?
Candidates can expect a pay range of $60,000 and $85,000 per year.
What employment applies to this position at Systimmune?
Systimmune lists this role as a Full-time position.
What experience level is required for this role at Systimmune?
Systimmune is looking for a candidate with "Entry-level" experience level.
What benefits are offered by Systimmune for this role?
Systimmune offers following benefits: Health Insurance, Dental Insurance, Vision Insurance, Disability Insurance, Paid Holidays, Paid Vacation, Paid Sick Leave, 401k Matching/Retirement Savings, and Health & Wellness Programs for this position. Actual benefits may vary depending on the employer's policies and employment terms.
What is the process to apply for this position at Systimmune?
You can apply for this role at Systimmune either through Sonara's automated application system, which helps you submit applications 10X faster with minimal effort, or by applying manually using the direct link on the job page.