Research Lab Tech I

Site: The General Hospital Corporation

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

The Rivera laboratory is part of the MGH Pathology Department and MGH Cancer Center and we are also affiliated with the Broad Institute. Our work is focused on using genomic technologies to identify and characterize abnormal gene regulation pathways that drive cancer cells and new approaches to modulate them. Our studies involve the integration of biochemistry, cell biology and genome-wide profiling of chromatin and transcriptional states (such as ChIP-seq, ATAC-seq, RNA-seq, Hi-ChIP and HiC). Using these approaches, our laboratory has uncovered gene regulation networks and new mechanisms of chromatin regulation in a variety of tumor types, including medulloblastoma (Boulay et al, Cancer Discovery 2017) and Ewing sarcoma (Riggi et al, Cancer Cell 2014; Boulay et al, Cell 2017). We have also developed new technologies to study chromatin states associated with repetitive elements and disordered proteins (Tak et al, Cell Genomics 2022; Xing et al, Nature Biotechnology 2023. Research technicians will join a collaborative group of scientists working on cutting edge research.

Work will be performed in the laboratory of Dr. Miguel Rivera (Molecular Pathology Unit, Charlestown Navy Yard Research Center)

Qualifications

Principle Responsibilities

As members of the team, research technicians are expected to work closely with postdoctoral fellows and contribute experimentally to one or several research projects in the laboratory. Contributions will include: setting up and performing experiments, assisting with hypothesis generation, experimental design and data interpretation. Common assays include western blotting, qPCR, cloning, RNA/DNA isolation, genomic assays (e.g. ChIP-seq, RNA-seq), lentivirus production, general mammalian cell culture, compound screening.

Skiils and Competencies Required

Basic laboratory skills

Computer literacy

Good communication skills

Ability to work independently and as a member of a team

Must be able to multi-task

Education:

Bachelor's degree required

Field of Study/Additional Specialized Training:

Biology or a related field is required.

Experience: Laboratory experience is preferred in addition to class work.

Additional Job Details (if applicable)

Remote Type

Onsite

Work Location

149 Thirteenth Street Building 149

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

Pay Range

$20.16 - $29.01/Hourly

Grade

5

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

EEO Statement:

1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

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