Research Lab Tech I Research Neurology HV

Site: The Brigham and Women's Hospital, Inc.

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Job Summary

Summary

The Venkatesh Lab (www.venkateshlab.org) is seeking a highly motivated lab technician to join our pioneering research efforts in the field of cancer neuroscience. Our lab's exciting new area of research lies at the intersection of cancer biology and neuroscience - we focus on characterizing and therapeutically targeting electrical components of disease pathophysiologies. By improving our understanding of the cellular and molecular mechanisms involved in neuron-cancer communication and circuit formation in and outside of the brain, the Venkatesh Lab aims to harness the systems level microenvironmental dependencies of tumor growth to develop innovative therapeutic treatments.

Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data.

Does this position require Patient Care? No.

Essential Functions

• Perform laboratory experiments following established protocols and procedures.
• Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
• Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
• Record experimental data accurately and maintain organized records of procedures, protocols, and results.
• Compile and analyze data using appropriate statistical and analytical methods.
• Assist in data interpretation and presentation, contributing to research findings and reports.

Qualifications

Education

Bachelor's Degree Related Field of Study required

Experience

Prior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferred

Knowledge, Skills and Abilities

• Strong theoretical and practical knowledge of laboratory techniques and procedures.
• Familiarity with common laboratory equipment and instruments used in research experiments.
• Proficiency in data collection, analysis, and scientific software tools.
• Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
• Strong problem-solving skills and the ability to troubleshoot technical issues.
• Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

Additional Job Details (if applicable)

Research Support- 70%

• Operate specialized instruments such as sliding microtomes, vibrotomes, and cryostats to prepare tissue sections for various organs.
• Perform routine cell culture techniques, including cell passage, freezing, and thawing.
• Analyze and quantify microscopy results to support project goals and reporting.
• Troubleshoot and preform molecular biology techniques such as virus production, primer design, molecular cloning, and transfection.
• Perform techniques such as Western blotting, viral transduction, next-generation sequencing (NGS).
• Assist in microscopy imaging, including confocal and fluorescence microscopy.
• Learn, master, and implement surgical techniques commonly used in preclinical models.
• Optimize and troubleshoot immunofluorescence, immunohistochemistry, and in situ hybridization protocols.

Mouse Husbandry- 20%

• Responsible for the maintenance and care of laboratory mice including breeding, weaning, ear tagging, and allocation to lab members.
• Maintain up to date mouse records and reports on mouse census to supervisors.
• Necropsy and tissue harvesting from various mouse models.

Lab Upkeep- 10%

• Maintain a clean and well-organized work environment, ensuring proper storage of reagents, cells, and samples.
• Manage laboratory inventories, including ordering reagents and maintaining stock levels of commonly used consumables.
• Receive, store, and document reagents/packages
• Assist in ensuring compliance with institutional biosafety, animal care, and chemical safety regulations.
• Help maintain accurate lab documentation, including protocols, experimental records, and safety data sheets.

Qualifications:

• Bachelor's degree in biology or related life sciences major. 1-2 years of experience outside of coursework required.
• Demonstrated experience with tissue culture and aseptic technique.
• Experience with rodent handling, husbandry, and animal experiments.
• Must have demonstrated experience in molecular techniques, particularly cloning and transfection.
• Ability to design, execute, and troubleshoot protocols and experiments for various projects in the lab.
• Must be able to maintain detailed and accurate laboratory notebooks documenting experimental procedures, results, and observations.
• Compile, analyze, and present data in a timely fashion.

Remote Type

Onsite

Work Location

60 Fenwood Road

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

Pay Range

$20.16 - $29.01/Hourly

Grade

5

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

EEO Statement:

2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

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