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Senior Scientist

Repligen CorporationLebanon, NH

$115,000 - $145,000 / year

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Overview

Schedule
Full-time
Career level
Senior-level
Remote
On-site
Compensation
$115,000-$145,000/year
Benefits
Health Insurance
Dental Insurance
Vision Insurance

Job Description

Lead the design and optimization of next-generation affinity purification technologies for a wide range of biopharmaceutical modalities. This role combines high-throughput experimentation, data-driven process development, and cross-functional collaboration to deliver innovative purification solutions that accelerate bioprocessing performance and enable partner success.

"This role is expected to model our Leadership Behaviors-Integrity & Compliance, Customer Focus, Collaboration, Courage, Team Empowerment, and Accountability & Results-in all aspects of work."

Key Responsibilities

  • Design, develop, and optimize affinity chromatography-based purification processes for diverse biopharmaceutical modalities
  • Execute high-throughput chromatographic screening and apply DOE methodologies to accelerate process development
  • Analyze, interpret, and communicate complex datasets to drive decision-making and support partner adoption of new technologies
  • Collaborate cross-functionally with internal teams (chemistry, analytics, commercial) to deliver integrated purification solutions
  • Contribute to multiple development programs, ensuring timely execution and high-quality scientific output
  • Innovate and propose novel approaches to improve purification performance, selectivity, and scalability
  • Engage with external biopharma partners as a technical expert and scientific collaborator

Qualifications

  • MS or PhD in Biochemistry, Chemical Engineering, Biochemical Engineering, or related field
  • Minimum of 5 years of hands-on experience in downstream processing and protein purification; including FPLC
  • Experience across multiple modalities (e.g., proteins, enzymes, vaccines, VLPs, gene therapy vectors)
  • Expertise in chromatography method development, including automated/high-throughput systems
  • Strong proficiency with Design of Experiments (DOE) for process optimization
  • Working knowledge of analytical techniques (e.g., purity/impurity analysis, potency, stability assays)
  • Broad scientific understanding spanning separations, protein chemistry, and bioprocessing
  • Strong communication skills with the ability to translate data into clear, actionable insights
  • Self-motivated, collaborative, and effective in a fast-paced, innovation-driven environment

Our mission is to inspire advances in bioprocessing as a trusted partner in the production of biologic drugs that improve human health worldwide. Focused on cost and process efficiencies, we deliver innovative technologies and solutions that help set new standards in bioprocessing. The estimated salary range for this role, based in the United States of America is $115,000/yr. -$145,000/yr.

Compensation decisions are dependent on several factors including, but not limited to an individual's qualifications, location, internal equity, and alignment with market data. Additionally, employees are eligible to participate in one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts. All compensation and benefits information will be confirmed in writing at the time of offer.

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FAQs About Senior Scientist Jobs at Repligen Corporation

What is the work location for this position at Repligen Corporation?
This job at Repligen Corporation is located in Lebanon, NH, according to the details provided by the employer. Some roles may also include multiple work locations depending on the requirement.
What pay range can candidates expect for this role at Repligen Corporation?
Candidates can expect a pay range of $115,000 and $145,000 per year.
What employment applies to this position at Repligen Corporation?
Repligen Corporation lists this role as a Full-time position.
What experience level is required for this role at Repligen Corporation?
Repligen Corporation is looking for a candidate with "Senior-level" experience level.
What benefits are offered by Repligen Corporation for this role?
Repligen Corporation offers following benefits: Health Insurance, Dental Insurance, Vision Insurance, Paid Vacation, 401k Matching/Retirement Savings, and Health & Wellness Programs for this position. Actual benefits may vary depending on the employer's policies and employment terms.
What is the process to apply for this position at Repligen Corporation?
You can apply for this role at Repligen Corporation either through Sonara's automated application system, which helps you submit applications 10X faster with minimal effort, or by applying manually using the direct link on the job page.