Senior Scientist, Antibody Discovery

SystImmune, Inc.Bothell, WA

$110,000 - $130,000 / year

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Overview

Schedule

Full-time

Career level

Senior-level

Remote

On-site

Compensation

$110,000-$130,000/year

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Job Description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Bothell, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

We are seeking a highly skilled and motivated Senior Scientist to join our Antibody Discovery Group. The successful candidate will play a critical role in advancing our antibody discovery efforts through various techniques, including immunogen design, B-cell sorting, flow cytometry, ELISA, and yeast library screening. This position offers an exciting opportunity to work in a dynamic and innovative environment focused on the development of novel therapeutic antibodies.

Responsibilities

Design and execute antibody discovery campaigns from immunization to lead delivery.
Perform high throughput sorting to isolate specific B cell populations.
Design, execute, and analyze FACS experiments to validate and characterize antibodies.
Develop, optimize, and perform assays (ELISA, BLI, flow cytometry) for antibody screening and specificity testing.
Conduct yeast display library screening to identify and analyze antibody candidates.
Analyze experimental data and prepare detailed reports and presentations.
Work with cross-functional teams and contribute to project planning and strategy.
Maintain accurate records, ensure safety compliance, and contribute to lab organization.

Qualifications

Ph.D. in Immunology, Molecular Biology, Biochemistry, or a related field with 5+ years of industry experience, including some applicable post doctoral research experience.
3-7 years of hands-on experience in B-cell sorting and screening through flow cytometry, ELISA and bio-layer interferometry.
Proficiency in flow cytometry and cell sorting techniques.
Experience in biolayer interferometry (affinity, avidity, binning) or similar assays.
Strong background in ELISA assay development and optimization.
A proven track record of working with Sony cell sorters or similar instruments is preferred.
Experience with single-cell analysis platforms (i.e., Beacon) is highly desirable.
Experience in antibody discovery and development is highly desirable.
Experience in NGS library preparation and BCR repertoire analysis is a plus.
Expertise in molecular biology techniques related to yeast display libraries, including preparation, culture and screening is preferred.

Compensation and Benefits:

The expected base salary range for this position is $110,000 - $130,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's level qualifications, experience, and skills.

While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.

SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.

We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

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FAQs About Senior Scientist, Antibody Discovery Jobs at SystImmune, Inc.

What is the work location for this position at SystImmune, Inc.?

This job at SystImmune, Inc. is located in Bothell, WA, according to the details provided by the employer. Some roles may also include multiple work locations depending on the requirement.

What pay range can candidates expect for this role at SystImmune, Inc.?

Candidates can expect a pay range of $110,000 and $130,000 per year.

What employment applies to this position at SystImmune, Inc.?

SystImmune, Inc. lists this role as a Full-time position.

What experience level is required for this role at SystImmune, Inc.?

SystImmune, Inc. is looking for a candidate with "Senior-level" experience level.

What benefits are offered by SystImmune, Inc. for this role?

SystImmune, Inc. offers following benefits: Health Insurance, Dental Insurance, Vision Insurance, Disability Insurance, Paid Holidays, Paid Vacation, Paid Sick Leave, 401k Matching/Retirement Savings, and Health & Wellness Programs for this position. Actual benefits may vary depending on the employer's policies and employment terms.

What is the process to apply for this position at SystImmune, Inc.?

You can apply for this role at SystImmune, Inc. either through Sonara's automated application system, which helps you submit applications 10X faster with minimal effort, or by applying manually using the direct link on the job page.