Staff Pathologist - Phoenix

Help us change lives

At Exact Sciences, we're helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you're working to help others.

Position Overview

Our Phoenix laboratory performs advanced molecular diagnostics supporting the OncoExTra + IHC, and OncoDetect testing programs. These assays leverage next-generation sequencing (NGS) and circulating tumor DNA technologies to provide comprehensive genomic insights that help guide therapy selection, monitor minimal residual disease, and inform treatment decisions for patients with cancer.

As a Staff Pathologist, you will play a key role in the interpretation, validation, and clinical reporting of molecular diagnostic results while collaborating closely with cross-functional teams across laboratory operations, bioinformatics, clinical development, and medical affairs. Our Phoenix laboratory is CAP-accredited and CLIA-certified, performing high-complexity molecular testing that supports precision oncology initiatives and clinical research programs.

This role follows a digital workflow/ hybrid model, with physicians working approximately three weeks remote and one week per month on-site in Phoenix to support laboratory operations, case sign-out, and collaboration with the local team.

Essential Duties

include but are not limited to the following:

• Provides diagnostic pathology expertise through the review and interpretation of laboratory data and tissue specimens in accordance with clinical, regulatory, and quality standards.
• Interpret and sign out solid tumor molecular diagnostic cases
• Interpret and sign out IHC biomarkers (PDL1, HER2)
• Perform H&E assessment of tumor cellularity
• Contribute to assay validation, workflow optimization, and quality improvement initiatives
• Provides pathology professional services to support pathology related questions from stakeholders; including, but not limited to, Medical Affairs, Customer Care, pathologists, oncologists, laboratories, and other clinical providers.
• Models positive relationships with key internal collaborators through regular connections and participation in periodic meetings with teams like Histology, Lab Operations, Customer Service, Medical Affairs, Accessioning and Information Technology to ensure high quality and efficient operations.
• Understands Exact Sciences' Laboratory Management requirements, which are informed by Clinical Laboratory Improvement Amendments (CLIA) and College of American Pathologists (CAP) regulations.
• Participate in the development, optimization, and implementation of new procedures for pathology and histology function.
• Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform keyboarding/mousing for approximately 80% of a typical working day.
• Ability to lift, carry, push or pull up to 10 pounds within the typical working day.

Minimum Qualifications

• Doctor of Medicine (M.D.).
• Board-certified in Anatomical and Clinical Pathology.
• Completion of a Surgical Pathology and/or Cytology Fellowship.
• 3+ years of clinical practice experience.
• Demonstrated ability to perform diagnostic surgical pathology skills.
• Demonstrated ability to provide a strong patient-centric and customer service orientation.
• Authorization to work in the United States without sponsorship.
• Demonstrated ability to perform the Essential Duties of the position with or without accommodation.

Preferred Qualifications

• Arizona License to practice medicine.
• Subspecialty training in breast, urologic, or molecular pathology in a prior industry.

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Salary Range:

$227,000.00 - $341,000.00

The annual base salary shown is a national range for this position on a full-time basis and may differ by hiring location. In addition, this position is bonus eligible.

Exact Sciences is proud to offer an employee experience that includes paid time off (including days for vacation, holidays, volunteering, and personal time), paid leave for parents and caregivers, a retirement savings plan, wellness support, and health benefits including medical, prescription drug, dental, and vision coverage. Learn more about our benefits.

Our success relies on the experiences and perspectives of a diverse team, and Exact Sciences fosters a culture where all employees can develop personally and professionally with a sense of respect and belonging. If you require an accommodation, please contact us here.

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We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to disability, protected veteran status, and any other status protected by applicable local, state, or federal law.

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