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Postdoctoral Research Associate - Structural Biology-logo
Postdoctoral Research Associate - Structural Biology
St. Jude Children's Research HospitalMemphis, Tennessee
A postdoctoral research associate position is available in the lab of Tanja Mittag in the Department of Structural Biology. Project Description: The Mittag laboratory invites applications for a Postdoctoral Research Associate Position to work on the biophysics of sequence–structure–function relationships of intrinsically disordered protein regions (IDRs). IDRs use different types of sequence-encoded grammars, and these are often tied to their subcellular localization and the biological processes they are involved in. We have extensively characterized how the molecular grammar of prion-like low-complexity domains encode conformational preferences and give rise to condensates with specific emergent properties (e.g., Martin et al. Science 2020, Bremer et al. Nat Chem 2022, Farag et al. Nat Commun 2023; Alshareedah et al. Nat Physics 2024; Posey et al JACS 2024). In this project, we will define sequence-encoded conformational preferences, driving force for phase separation and emergent properties of other types of IDR sequences. Position Responsibilities: The successful candidate will help shape the direction of the research and will use in vitro biophysical and biochemical studies to characterize the conformational properties of IDRs and the properties of the condensates they form. The candidate will interface with trainees and staff scientists in the Mittag lab, and with collaborators in a highly collaborative, interdisciplinary environment that will support their career development. Minimum Education and/or Training: The successful candidate should have a Ph.D. in biophysics or a related discipline. The candidate should demonstrate an academic record of excellence, and a strong interest in the growing field of biomolecular condensates. Special Skills, Knowledge, and Abilities: Experience with quantitative biophysical techniques such as NMR spectroscopy and/or small-angle X-ray scattering is required to capitalize on the opportunities of this project. About the lab and St. Jude: The successful candidate will join a highly collaborative laboratory focused on elucidating the biophysics, biochemistry and function of condensates in the Department of Structural Biology, with access to state-of-the-art instrumentation and expertise in the Department of Structural Biology and across the hospital. St. Jude Children’s Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The first and only National Cancer Institute (NCI)-designated Comprehensive Cancer Center devoted solely to children. Our 300 faculty work across the spectrum of basic, translational, clinical, and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine. St. Jude is ranked on Fortune Magazine’s “Best Workplaces in Health Care & Biopharma” and Glassdoor’s “Best Places to Work,” and is located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food and culture. We are in pursuit of the brightest minds in biomedical sciences, individuals poised to contribute to our research progress. Other than access to top-quality scientists and mentors, as a postdoctoral trainee at St. Jude, you will have: A Blend of Academic Freedom and Industrial Efficiency : Access to shared resources and facilities led by expert scientists, coupled with cutting-edge technology, accelerates research productivity. Customized Professional and Career Growth: Experience specifically designed programs to enhance professional growth and career readiness empowering postdocs for success beyond their training. This includes access to grant writing workshops, individual development plans, teaching and mentoring opportunities, non-research career advancement programs, professional development allowance, and so much more. Competitive Compensation: Embark on your journey with a competitive salary starting at $72,500 a year, comprehensive benefits and generous relocation assistance, reflecting our commitment to recognize and invest in talent. A Sense of Community: St. Jude fosters a vibrant postdoc community that supports a well-balanced life. A dynamic environment promotes connections and camaraderie among postdocs from all backgrounds. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Posted 2 weeks ago

Faculty positions - Department of Chemical Biology and Therapeutics-logo
Faculty positions - Department of Chemical Biology and Therapeutics
St. Jude Children's Research HospitalMemphis, Tennessee
St. Jude Children's Research Hospital The Department of Chemical Biology and Therapeutics (CBT) at St. Jude Children’s Research Hospital invites applications for an Open Rank Faculty position in Chemical Biology. We seek creative applicants with bold vision and demonstrated excellence in research at the interface of Chemistry, Biology and Medicine. The faculty rank of candidates will be commensurate with their experience. St. Jude offers generous start-up packages, including full salary for faculty and support staff; equipment funds; state-of-the-art chemical and computational facilities; and access to cutting-edge institutional shared resources. A curriculum vitae, concise summary of research contributions with links to three publications, well-articulated research plan (3-5 pages), and names and contact information of three references (for assistant member positions) should be submitted directly online. Successful candidates should have a PhD, MD, or MD-PhD in Chemistry, Chemical Biology, Chemical/Biological Engineering or related academic disciplines. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Posted 30+ days ago

Teaching Assistant - Biology-logo
Teaching Assistant - Biology
Mercer UniversityMacon, Georgia
Application Instructions: Active Student Employees : If you are a current Student Employee or have previously worked in a student position, you must apply from your existing Workday account. Do not apply from the external careers website . Log in to Workday and type Find Jobs in the search . Locate the position and click Apply . External Applicants: Please upload your resume on the Apply screen. Your application will automatically populate your resume details, and you may verify and update data on the My Information page. IMPORTANT: Please review the job posting and fully complete all sections of the application. You will not be able to modify your application after you submit it . Job Family: Student Regular Wage Department: Biology Supervisor: Bryan Bill Job Title: Teaching Assistant - Biology Job Description: Teaching Assistants will assist the instructor in providing classroom instruction and organizing the delivery of instructional materials. Tasks include answering questions from students related to the lab experiments Help distribute lab supplies to the class Possess operational knowledge of computers and procedures for re-starting, shutting down, and basic troubleshooting technical issues Enthusiastic and willing to assist other students Assist in the clean-up of used lab materials and equipment at the end of lab Lab sections available: BIO-102, 131, 171, 172, 280, 303, and 460L Requirements: Must seek approval and obtain recommendation by the professor for the course(s) you intend to TA Must have successfully completed the course(s) that you intend to work as a TA Must be dependable and show up on-time Pay rate : $10.80 per hour Scheduled Hours: 3 Start Date: 08/11/2025 End Date: 05/8/2026

Posted 6 days ago

A
Scientist I/Scientist II, Chemical Biology (Must Have Intact Mass Spectrometry Experience)
Antares TherapeuticsBoston, Massachusetts
Job Summary Antares Therapeutics is seeking a motivated and detail-oriented Scientist I/ II to join our Chemical Biology team. As a member of the team, you will be responsible for designing and executing experiments to identify and validate novel therapeutic targets, elucidate mechanism(s) of inhibition, enable detailed biophysical characterization of molecular interactions involved and perform screens for hit identification and SAR advancement. Achieving these objectives will involve innovative chemoproteomic methodologies and the utilization of advanced HPLC and mass spectroscopy instrumentation. This position offers a unique opportunity to work in a collaborative, fast-paced environment at the intersection of chemistry and biology. Key Responsibilities Apply chemical biology techniques (e.g., activity-based protein profiling, covalent-probe evaluation, MS-based biophysical compound library screening, or other advanced proteomic approaches) to identify and validate potential therapeutic targets and to identify, characterize and support progression of hit compounds. Advance and develop peptide/protein sample preparation approaches designed for target enrichment and throughput Analyze experimental data, interpret results, and present findings at internal meetings. Maintain accurate and detailed laboratory records as well as up-to-date electronic notebooks. Contribute to the day-to-day operations of the chemical proteomics group, including inventory management, reagent ordering & preparation, HPLC and mass spectrometer instrument calibration and routine maintenance. Professional Experience/Qualifications B.S. in Chemical Biology, Biochemistry, Molecular Biology, Chemistry, or a related field with 8+ years of relevant research experience in academia/industry OR M.S. with 4+ years of relevant research experience in academia/industry An understanding of protein chemistry with experience performing biochemical/biophysical assays using recombinant proteins and preparation of peptide samples from different cell and tissue sources. Hands-on experience with liquid chromatography and mass spectrometry instrumentation operation and maintenance is required Familiarity with best practices for proteomics data analyses, their underlying statistical principles, and methods for accurate quantitation. A highly engaged, self-starter who is creative, innovative, communicative and possesses both a goal/results-orientated style

Posted 6 days ago

Sr Director, Skeletal / Bone Biology for Musculoskeletal Therapeutic Area-logo
Sr Director, Skeletal / Bone Biology for Musculoskeletal Therapeutic Area
BioMarin PharmaceuticalSan Rafael, California
Description Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best – people with the right technical expertise and a relentless drive to solve real problems – and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we’ve produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Worldwide Research and Development From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases. Role Description: We are seeking a highly motivated and agile Senior Director with extensive experience in skeletal biology and disease to join the Musculoskeletal Therapeutic (MSK) Area in BioMarin Research. The Senior Director will use their skeletal biology and disease background to influence and guide the development of ongoing and new therapeutic programs in the skeletal disease space. The role reports into the Head of the Musculoskeletal Therapeutic Area as a member of the Therapeutic Area Leadership Team. The role will have extensive interactions and partnership within Research and across the company. The successful candidate will have deep experience and professional connections in the skeletal biology and disease community to facilitate and guide BioMarin’s future developments in this space. The ideal candidate will have a proven track record of collaboration and partnership on complex scientific research efforts in skeletal disease. The role will have two key areas of focus: 1) influencing the internal preclinical skeletal disease therapeutic pipeline and 2) initiating, guiding or leading external partnerships with leading experts to evaluate novel therapeutic approaches. The ideal candidate will have >15+ years of skeletal disease and biology research experience, Biotech/Pharma industry and therapeutic development experience is desirable . While management experience is desirable, the ability to work collaboratively with a wide array of partners is critical. Responsibilities : Identification, initiation, and monitoring external partnerships: Demonstrate ability to engage with industry and academic external scientific community to build a network of relationships that catalyze progress in identifying therapeutic strategies to skeletal diseases. Influence and execute on external partnerships aimed at addressing key technical limitations for therapy development for skeletal diseases with high unmet needs. Identify and launch key external collaborations to explore novel skeletal disease therapeutics. Navigate internal governance on new project initiation and resourcing. Bringing skeletal biology expertise to guide and influence novel therapeutic programs: Effectively collaborate with both internal and external scientists on novel therapeutic programs for skeletal diseases. Lead with vision and purpose to influence the content and strategy of the internal skeletal disease pipeline in alignment with corporate objectives. Demonstrates organizational savvy and ability to mitigate risks across a portfolio of programs. Persuasively present complex information to various audiences and constructively negotiate desired outcomes with key stakeholders. Produce and advise on the design of program strategies to efficiently develop novel treatments. Actively seek knowledge of therapeutic innovations to keep BioMarin on the cutting edge of skeletal condition therapeutic development. Serve as a key expert to guide evaluation and diligence on business development opportunities. General Requirements: Acknowledges, integrates, and leverages different perspectives and demonstrates commitment to diversity, equity, and inclusion. Must have excellent troubleshooting, organization, and planning skills, and the ability to work under timeline in a fast-paced environment. Management experience and skills are important to demonstrate interpersonal skills and for potential to grow into team oversight/management . Excellent written and oral communication skills to effectively share scientific findings with peers and senior leadership. Actively models clear communication and encourages constructive feedback. Excellent documentation skills using Electronic Lab Notebooks. Follow instructions and work independently to effectively manage time and prioritize tasks to ensure all assignments are completed on or before deadlines. Strong analytical, problem-solving, and decision-making skills. Passion for contributing your scientific skills to develop therapies for patients in need. Able to take setbacks in stride and champion change with shifting timelines and priorities. Requires minimal direction of day-to-day responsibilities, including collaboratively working with multidisciplinary teams. Some “off-core business hours” work required. Some travel for scientific conferences and managing external collaborators Complete all company training requirements. Education and Experience Requirements: PhD and/or MD in a related subject area with demonstrated research experience in skeletal biology. Extensive academic and/or industrial experience in skeletal biology. Demonstrated experience in skeletal biology/disease research in academia or industry with an extensive publication record. This position is full-time on-site or hybrid and based in San Rafael, CA Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Posted 2 weeks ago

Adjunct, Biology-logo
Adjunct, Biology
Saint Joseph's UniversityLancaster, California
Position Title: Adjunct, Biology Time Type: Part time Position Summary and Qualifications: Saint Joseph's University Department of Biology has an ongoing need for highly qualified adjunct faculty to staff a variety of courses each semester. Professionals with experience and a passion for teaching at the undergraduate level will be given preference. Part-time adjunct faculty may instruct one or two courses each semester on an "as needed" basis. Courses available for adjunct staffing are offered during the day and also in the evening. Courses available for adjunct staffing may include, but are not limited to: Anatomy and Physiology, Microbiology, Nutrition and other related courses. This is Lancaster Campus. For further information about the Department of Biology, please visit our website at: http://www.sju.edu/academics/cas/biology/ Essential Duties & Responsibilities: Develop and deliver instructional materials such as lectures, lab activities, and assessments Hold regular office hours to support students Create, Administer, and Grade assignments, quizzes, lab reports, and exams Maintain accurate records of student progress in the course Minimum Qualifications: Master's degree in Biology or a closely related field required (Ph.D. preferred) Prior teaching experience at the college level strongly preferred Excellent oral and written communication skills Ability to effectively explain complex concepts to students Strong organizational and classroom management skills Required Documents ( All documents may be attached to the "Resume/CV" field.) : Cover Letter/Letter of Interest Resume/Curriculum Vitae List of References Saint Joseph’s University is a private, Catholic, Jesuit institution and we expect members of our community to be knowledgeable about – and to make a positive contribution to – our mission. Saint Joseph’s University is an equal opportunity employer that seeks to recruit, develop and retain a talented and diverse workforce. The University is committed to the diversity of its faculty and staff so that our students, our disciplines and our community as a whole can benefit from the multiple perspectives it offers. The University seeks qualified candidates who share our commitment to equity, diversity and inclusion. EOE Saint Joseph’s University prohibits discrimination on the basis of sex in its programs and activities, including admission and employment, in accordance with Title IX of the Education Amendments of 1972. The Title IX Coordinator is responsible for overseeing compliance with Title IX and other civil rights laws and regulations. To contact the Title IX Coordinator, e-mail titleix@sju.edu, visit Campion Student Center suite 243, or call 610-660-1145. To learn more about the University’s Title IX policies, the process for filing a report or formal complaint of sex discrimination, sexual harassment, or other form of sexual misconduct, and the University’s response to reports and/or formal complaints, please visit www.sju.edu/titleix . Inquiries may also be directed to the Federal agency responsible for enforcing Title IX, the U.S. Department of Education Office for Civil Rights .

Posted 2 weeks ago

Chair, Department of Dermatology & Cutaneous Biology at Thomas Jefferson University-logo
Chair, Department of Dermatology & Cutaneous Biology at Thomas Jefferson University
Thomas Jefferson UniversityPhiladelphia, Pennsylvania
Job Details Thomas Jefferson University seeks a collaborative and engaging academic physician leader to serve as the next Chair of the Department of Dermatology & Cutaneous Biology at Sidney Kimmel Medical College, located on the University’s 13-acre campus in Center City Philadelphia. Job Description Reporting to the Dean of Sidney Kimmel Medical College, the Chair will oversee all departmental programs, including an ACGME-accredited Dermatology residency and Dermatopathology fellowship, ensuring outstanding education, clinical training, and research opportunities for the Department’s residents and fellows, as well as students at the Medical College. The Chair will oversee a growing academic practice and will ensure exceptional care is provided at the Department’s 3 outpatient offices and Thomas Jefferson University Hospital – Jefferson Health’s flagship quaternary care hospital and the University’s primary teaching hospital. The Department’s academic practice includes 11 clinical faculty, 3 advanced practice providers, 13 residents and fellows, and 2 histotechnologists. Additionally, the successful candidate will play a key strategic role in "driving systemness” for the University’s health system partner – Jefferson Health, which has grown from a three-hospital, urban academic medical center to a network of 32 hospitals, comprised of both employed and independent physician practices contractually-aligned with Jefferson. In line with Jefferson’s commitment to providing enhanced access to value-based care, the Chair will pursue strategic opportunities to effectively scale the value proposition of a growing system, while ensuring the delivery of high-quality care, aligned with network standards and expected by Jefferson patients. The full, comprehensive position description can be found here . Qualifications An academic career trajectory with increasing levels of administrative responsibilities, ideally culminating in serving as Chair, Vice Chair, Chief or other senior leadership role for a Department of Dermatology. A demonstrated ability to advance tripartite clinical, education, and research missions – including a strong record of teaching and program administration; leading care quality improvement initiatives; supporting the growth, development, mentorship, and well-being of faculty, clinicians, and trainees; and facilitating research with a working understanding of the supporting infrastructure and nuances of clinical research. Experience with the operational and financial management aspects of administering a department, including prior responsibilities for budget management, strategic planning, and resource management. A record of scholarship and academic accomplishments which merits appointment at the rank of associate or full professor at Sidney Kimmel Medical College. An MD/DO or equivalent international degree, current board certification in Dermatology, and licensed or eligible to practice in the state of Pennsylvania. For full consideration, applicants should submit a Statement of Interest (see guidance below) and detailed c urriculum vitae to: Jennifer.Rumain@jefferson.edu by June 2, 2025 . Confidential inquiries, expressions of interest, and nominations can be submitted to the same address. Applications will be accepted until the position is filled. In their Statement of Interest , applicants should highlight their academic and clinical leadership experience and accomplishments and are encouraged to specifically address how they’ve contributed to: Strategically enhancing patient access to meet the evolving needs of patients and communities. Standardization of clinical care or other efforts to ensure consistent delivery of high-quality dermatologic care. Growing research (clinical and translational) or facilitating opportunities for research collaboration, e.g., expanding clinical trial opportunities by leveraging a growing clinical and community footprint. Innovative and strategic ways to s upport, develop, and recruit faculty and clinicians in response to the challenges facing academic dermatology. Ensuring health equity and/or advancing diversity, equity, and inclusion. Thomas Jefferson University and Hospitals is an Equal Opportunity Employer. Jefferson values diversity and encourages applications from individuals of diverse backgrounds, including but not limited to women, members of minority groups, LGBTQ individuals, individuals with disabilities, and veterans. Work Shift Workday Day (United States of America) Worker Sub Type Regular Primary Location Address 833 Chestnut Street, Philadelphia, Pennsylvania, United States of America Nationally ranked, Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value. Jefferson is more than 65,000 people strong, dedicated to providing the highest-quality, compassionate clinical care for patients; making our communities healthier and stronger; preparing tomorrow's professional leaders for 21st-century careers; and creating new knowledge through basic/programmatic, clinical and applied research. Thomas Jefferson University , home of Sidney Kimmel Medical College, Jefferson College of Nursing, and the Kanbar College of Design, Engineering and Commerce, dates back to 1824 and today comprises 10 colleges and three schools offering 200+ undergraduate and graduate programs to more than 8,300 students. Jefferson Health , nationally ranked as one of the top 15 not-for-profit health care systems in the country and the largest provider in the Philadelphia and Lehigh Valley areas, serves patients through millions of encounters each year at 32 hospitals campuses and more than 700 outpatient and urgent care locations throughout the region. Jefferson Health Plans is a not-for-profit managed health care organization providing a broad range of health coverage options in Pennsylvania and New Jersey for more than 35 years. Jefferson is committed to providing equal educa­tional and employment opportunities for all persons without regard to age, race, color, religion, creed, sexual orientation, gender, gender identity, marital status, pregnancy, national origin, ancestry, citizenship, military status, veteran status, handicap or disability or any other protected group or status.

Posted 6 days ago

Biology Lab Assistant-logo
Biology Lab Assistant
Mercer UniversityMacon, Georgia
Application Instructions: Active Student Employees : If you are a current Student Employee or have previously worked in a student position, you must apply from your existing Workday account. Do not apply from the external careers website . Log in to Workday and type Find Jobs in the search . Locate the position and click Apply . External Applicants: Please upload your resume on the Apply screen. Your application will automatically populate your resume details, and you may verify and update data on the My Information page. IMPORTANT: Please review the job posting and fully complete all sections of the application. You will not be able to modify your application after you submit it . Job Family: Student Work Study Department: Biology Supervisor: Brooke Cabrera Job Title: Biology Lab Assistant Job Description: Student Lab Assistants are responsible for assisting a lab coordinator with basic lab maintenance such as setting up and taking down laboratory materials, cleaning lab spaces and materials. Requirements: Canidate must be majoring and/or minoring in Biology or a closely related field. Previous lab experience and basic lab safety knowledge is strongly preferred but not required. Must work well with others. Pay rate starts at $10.80/ hour. Please submit resume with application. Assists with Intro Biology, Genetics, Eukaryotic Cell, Research area duties/tasks. Scheduled Hours: 6 Start Date: 01/6/2025 End Date: 05/30/2025

Posted 3 weeks ago

W
Assistant Professor of Molecular Biology and Biochemistry
WU Wesleyan UniversityMiddletown, Connecticut
The Department of Molecular Biology and Biochemistry at Wesleyan University seeks a tenure-track Assistant Professor of Molecular Biology and Biochemistry beginning July 1, 2026. The candidate will develop an independent research program supported by extramural funding that integrates current molecular genetics, biochemical or biophysical approaches to address fundamental problems in molecular biology. The minimum requirement is a Ph. D. in molecular biology or a related field. The successful candidate will likely have postdoctoral experience and demonstrated excellence in research and teaching. We seek an individual who can contribute to both our undergraduate and graduate course curriculum. The successful applicant will teach one course each semester and facilitate a journal club or graduate seminar. The new hire will establish their lab in our brand-new science building and participate in our Ph.D. training program and cross-disciplinary initiatives in the life sciences. Additional duties include advising and mentoring students, as well as participating in faculty governance at the departmental and university level. Wesleyan is a highly selective liberal arts college that values both scholarship and teaching, has a strong, diverse undergraduate student body, and offers a generous sabbatical program and competitive salaries and benefits. A complete application includes a cover letter, curriculum vitae, publications, a statement of research plans, a statement of teaching interests, course syllabi and teaching evaluations (if available), and email addresses for three referees from whom we will obtain confidential letters of recommendation. In the cover letter, applicants should describe how they will embrace the college's commitment to fostering an inclusive community. Applications should be submitted online at https://wesleyan.wd5.myworkdayjobs.com/careers . Applications completed by October 1, 2025 will receive full consideration. Please contact Mary Readinger by email ( mreadinger@wesleyan.edu ) or phone at 860-685-2409 if you have any questions about the application process. Work Location: On Campus All offers to external applicants are contingent on the candidate’s completion of a pre-employment background check screening to the satisfaction of Wesleyan University. Wesleyan University, located in Middletown, Connecticut, does not discriminate on the basis of race, color, religious creed, age, gender, gender identity or expression, national origin, marital status, ancestry, present or past history of mental disorder, learning disability or physical disability, political belief, veteran status, sexual orientation, genetic information or non-position-related criminal record. We welcome applications from women and historically underrepresented minority groups. Inquiries regarding Title IX, Section 504 or any other non-discrimination policies should be directed to Vice President for Equity and Inclusion, Title IX and ADA/504 Coordinator. Wesleyan University complies with the Clery Act and maintains records of campus crime statistics and security policies. Copies of Wesleyan University’s Clery Act Report are available on request and online at https://www.wesleyan.edu/publicsafety/clery.html . Experience is taken into consideration in the determination of salary offers. For more information visit https://www.wesleyan.edu/hr/handbook/compensation-practices/index.html Wesleyan offers a broad range of employee benefits and development opportunities, including comprehensive group insurance plans, wellness programs and incentives, generous paid time off and retirement plans, flexible work schedules, employee and dependent tuition programs for those who qualify. Detailed information on the benefits of working at Wesleyan is located at: https://wesleyan.edu/hr/careers/prospective-resources.html .

Posted 2 weeks ago

Scientist I, Small Molecule Assay Development (Biochemistry / Cell Biology)-logo
Scientist I, Small Molecule Assay Development (Biochemistry / Cell Biology)
1910 GeneticsBoston, Massachusetts
Company Overview 1910 Genetics is a Series A stage biotechnology company that is pioneering a novel Input-Transform-Output (ITO ™ ) platform as the first ever horizontal AI infrastructure for drug discovery. In a crowded space with hundreds of AI drug discovery companies, 1910’s ITO ™ platform is differentiated by: Modality agnostic drug discovery: our platform is capable of designing both small molecule and large molecule therapeutics across all disease areas, with an initial focus on neuroscience, oncology, and autoimmune diseases. Proprietary massive multimodal data, which overcomes the data scarcity problem that prevents frontier AI models from being utilized for drug discovery. Multi-AI agent systems that include a robust collection of frontier AI/ML models, each of which works in a task-oriented manner to achieve the multi-parameter optimization problem of drug discovery and development. A state-of-the-art (SOTA) fully-automated, high throughput wet laboratory in the premier Boston Seaport District for both data generation for AI model training as well as validation of the safety and efficacy of drug candidates that are outputted by our frontier AI models. An unprecedented partnership with Microsoft, which positions 1910 as the only biotech/pharma company leveraging Azure Quantum Elements, a groundbreaking, AI-driven, high performance computing (HPC) cloud architecture for advanced AI. Bespoke conversational AI chatbots that provide a customer friendly UI/UX to access our platform for specific drug discovery tasks. Being the only biotech company helping pharma companies integrate 6 core areas of AI infrastructure. 1910 Genetics is looking for an In Vitro Pharmacology Assay Scientist to design, develop and execute assays to measure the activity of small molecules on specific biological targets, such as proteins or cells. This position requires a strong background in molecular biology and biochemistry, along with experience in laboratory techniques and data analysis. The ideal candidate will have experience in small molecule discovery and characterization. Role Responsibilities Design, develop and execute in vitro biological assays to measure the activity of small molecules on specific biological targets, such as proteins or cells Adapt and validate assays to apply laboratory automation to test libraries of small molecules quickly, reliably and efficiently Perform data analysis and interpretation of assay results to identify promising molecules for further development Collaborate with cross-disciplinary scientists to refine assays to deliver program objectives Maintain detailed records of experimental procedures and results in electronic lab notebook Present experimental results/progress in timely manner and contribute to scientific discussion in group meetings Collaborate with cross-functional teams, including AI Research and Computational Chemistry to discuss project updates as well as ensure the project milestones and timelines are met Assist laboratory operations, including maintenance of equipment, reagent tracking and monthly inspections for safety equipment Develop and execute standard operating procedures and best practices to enhance lab efficiency and productivity Contribute to the preparation of scientific reports, presentations, and publications. Stay current with scientific literature and emerging technologies in the fields of large and small molecule research Qualifications PhD in Biology with a focus on Molecular Biology, Biochemistry, Cell Biology, In Vitro Pharmacology, Biomedical Sciences or a related field Postdoctoral experience or relevant industry experience in drug discovery or In Vitro Pharmacology Strong understanding of molecular biology, biochemical, and cell-based assays and their applications in drug development Familiarity with signal transduction pathways in relevant therapeutic areas such as Immunology & Inflammation, neuroscience, oncology, and cardiometabolic diseases Experience in immune cell isolation and cell-line engineering and assay development Excellent problem-solving, critical thinking, and data analysis skills Ability to work independently and as part of a collaborative team in a fast-paced and dynamic research environment Strong track record of research accomplishments, as evidenced by publications in scientific journals #LI-Onsite Diversity and Inclusion (1910’s Promise) At 1910, we believe that a diverse, equitable, and inclusive workplace furthers relevance, resilience, and longevity. We encourage people from all backgrounds, ages, abilities, and experiences to apply. 1910 is proud to be an equal-opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status. If, due to a disability, you need an accommodation during any part of the interview process, please let your recruiter know. While 1910 supports visa sponsorship, sponsorship opportunities may be limited to certain roles and skills. Benefits and Perks Competitive compensation package Above market benefits Generous vacation and parental leave Super cool team building activities Great colleagues

Posted 30+ days ago

Principal Scientist/Director, Cancer Biology-logo
Principal Scientist/Director, Cancer Biology
General ProximitySan Francisco, Mississippi
tl;dr General Proximity is a seed-stage startup developing the next generation of induced proximity medicines (IPMs). Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges, which have remained unapproachable to other modalities for decades. We are seeking a first-rate cancer biologist to help us pioneer this uncharted frontier of drug discovery. Our Story A long-standing challenge in drug discovery is the development of molecules capable of modulating difficult or "undruggable" targets. Disease-causing proteins can be dysfunctional in many different ways, but our armamentarium for fixing them is quite limited. The most common mechanism of action for FDA-approved drugs is inhibition [1] , but there are many other possible perturbation types whose potential remains unrealized. General Proximity is a seed-stage drug discovery company developing a novel platform technology to solve this problem. We make bifunctional drugs that induce the modification of drug targets by existing cellular machinery (rather than through direct modulation by the drug, the classical approach). Historically, the development of technologies that allow one to push new buttons in biology has been an incredibly fertile field for the discovery of new medicines[ 2 , 3 , 4 ], and our technology holds the same promise. The Position We are seeking an experienced cancer biologist to help lead our Biology Team. In this position, you will help lead and manage our Biology Team and work closely with our Platform Team in the development of our core drug discovery technology. Your responsibilities will include phenotypic assay development, establishing pre-clinical in vitro/in vivo studies, performing mechanistic studies on lead drug molecules, spearheading forays into new oncology indications, and grant writing. About You High Agency. Initiative, independence, and self-accountability are some of our most valued traits. Enthusiastic. We love people who are excited about what they are doing and are generally attempting to build a high-energy team. Intensity and Grit. Early-stage startups are hard. Drug discovery is doubly so. We are looking for candidates who have a demonstrated ability to stick with complex problems for the long haul, with a team that has your back along the way. Prosocial. We are here to create life-saving medicines for the patients who need it most. You should be, too. Qualifications & Nice-To-Haves PhD in Cancer Biology, Cell Biology, or related field. 5-7+ years of industry experience. Deep understanding of small-molecule drug discovery and its relationship to human disease. Exceptional leadership, interpersonal, and communication skills, with a track record of managing high-performing, multidisciplinary teams. Strong experience with : Mechanistic studies of cancer cell signaling and PTM analysis Phenotypic assay development for cancer drug discovery (low to high throughput) Small molecule drug development campaigns (hit discovery, hit validation, dose-response studies, MOA studies) Excellent cellular and molecular biology knowledge/experience (cancer cell lines, generation of stable cell lines using lenti/CRISPR systems, IP/pull down assays, RNA-Seq, flow cytometry, plasmid design) Proficiency in: Managing a team of exceptional scientists and research associates Target/indication selection Pre-clinical and IND-enabling studies Animal models of cancer (GEMM, orthotopic, xenograft models) Managing CROs for in vivo studies Grant writing Nice to have: Prior experience on teams that have successfully advanced research to the clinic Familiarity or experience with PROTAC/next-gen IPM technologies Experience with PPI techniques (e.g., BRET, APEX/BioID, AlphaScreen etc.) Benefits Strong equity incentives. We are looking for candidates who will bring a strong sense of ownership to drive their project areas forward, and we believe that you deserve to be compensated accordingly. Top tier medical, dental, and vision coverage + One Medical membership. 401(k) retirement plans. Education and health/fitness incentive programs. Meditation retreats—do a ten-day Vipassana retreat without counting towards vacation days. Reading budget! We will buy you books. 📚 Located in the MBC BioLabs at 135 Mississippi Street, an entrepreneurial hub full of the best scientists and operators the Bay Area has to offer. Our lab is a very short walk from the 22nd St Caltrain Station and a number of wonderful restaurants and cafés. About Us Work Hard/Play Hard. We believe time is our most valuable commodity, so we strive to create a culture that reflects this. We won’t drag you through unnecessary meetings or email you at 7 PM on a Saturday. When we're at work, we're there to get things done, and when we're off, we're really off. 🌴 Strong Communication. We like well-written documents over PowerPoints, OKRs over vague mission statements, and weekly one-on-ones over yearly reviews. Writing First. We have a "writing-first" culture. We believe that clarity of writing reflects clarity of thinking and that the benefits of well-written documentation in a scientific environment are innumerable: democratization of ideation and decision-making, increased reproducibility, quicker scaling and onboarding, and better company-wide alignment, to name a few. Growth. As an early-stage startup, we value scientists with an independent, can-do attitude. The more hats you can wear, the better. Our job as employers is to put you in positive feedback loops so you can grow in the direction of your choosing. Title and compensation commensurate with experience. Applications from candidates of diverse backgrounds, women, and members of underrepresented minority groups are particularly welcomed. We look forward to hearing from you. :) More info at jobs.generalproximity.bio

Posted 3 weeks ago

Software Engineer, Molecular Biology-logo
Software Engineer, Molecular Biology
BenchlingBoston, MA
Biotechnology is rewriting life as we know it, from the medicines we take, to the crops we grow, the materials we wear, and the household goods that we rely on every day. But moving at the new speed of science requires better technology. Benchling’s mission is to unlock the power of biotechnology. The world’s most innovative biotech companies use Benchling’s R&D Cloud to power the development of breakthrough products and accelerate time to milestone and market.  Come help us bring modern software to modern science. ROLE OVERVIEW We’re a full-stack web application development team focused on creating powerful, intuitive tools that support a broad range of scientific workflows. From designing DNA constructs and analyzing protein sequences to performing gene editing experiments and drawing chemical compounds, we build the features that help scientists better plan, execute, and understand their research. RESPONSIBILITIES Own end-to-end project development: Take ownership of projects from understanding product requirements and designs to planning, implementing, testing, and deploying solutions. You will handle the full lifecycle of features, from initial concept to final delivery. Collaborate with product managers and designers Write clean, maintainable code: Contribute to both frontend (React) and backend (Python) development, ensuring high-quality, scalable code that adheres to best practices and solid engineering principles. Refactor and manage technical debt: Take responsibility for improving and cleaning up existing code while building new features. Identify areas for technical improvement, ensuring long-term code maintainability and product scalability. Design and implement robust testing and metrics Collaboration with Other Engineers   Ownership and Accountability   Adaptability and Openness to New Challenges – Especially in a fast-paced, evolving field like life sciences, the ability to pivot, handle ambiguity, and quickly learn new technologies or domains could be important. Cross-functional Communication – Ability to work with other engineering teams as well and customer success QUALIFICATIONS 3+ years of professional software engineering experience. Solid understanding of software engineering best practices , including writing clean, maintainable code, testing, version control, and working within Agile workflows. Strong expertise in frontend development ( with React or similar frameworks ) and backend development ( with high level languages like Python ). Experience building scalable, user-friendly applications that support complex scientific workflows. Strong problem-solving skills , with the ability to iteratively improve solutions based on feedback and real-world performance. Experience collaborating with other engineers in a team setting. Ability to provide constructive feedback, perform code reviews, and work together on solving complex engineering problems. Excellent communication skills , with the ability to collaborate effectively with cross-functional teams (Product, Design, Data Science, etc.). A passion for learning and growth, especially in the life sciences or biotechnology space (no prior knowledge required, just a willingness to learn and adapt). NICE TO HAVE Familiarity with molecular biology or chemistry concepts or a strong interest in learning more about these fields. Proven ability to take product requirements and transform them into actionable technical plans and high-quality code. Experience managing technical debt and making decisions that balance product speed with long-term maintainability. Experience in building scalable and performant systems that meet user demands while ensuring reliability. Experience with layered architecture concepts and designing solutions that are robust, maintainable, and scalable. Experience working with platform and cross-functional teams to build comprehensive solutions that address multiple business needs beyond individual features. Ability to push back when necessary: Respectfully challenge product and design assumptions, advocating for technical solutions that improve product quality, scalability, and maintainability. Ability to mentor and contribute to team growth: Help onboard new team members and foster a collaborative, learning-driven environment, while contributing to the evolution of engineering practices and processes. HOW WE WORK Flexible Hybrid Work: We offer a flexible hybrid work arrangement that prioritizes in-office collaboration. Employees are expected to be on-site 3 days per week. SALARY RANGE Benchling takes a market-based approach to pay.  The candidate's starting pay will be determined based on job-related skills, experience, qualifications, interview performance, and work location. For this role the base salary range is $141,104 to $190,906 .  Total Compensation includes the following: Competitive total rewards package Broad range of medical, dental, and vision plans for employees and their dependents Fertility healthcare and family-forming benefits Four months of fully paid parental leave 401(k) + Employer Match Commuter benefits for in-office employees and a generous home office set up stipend for remote employees Mental health benefits, including therapy and coaching, for employees and their dependents Monthly Wellness stipend Learning and development stipend Generous and flexible vacation Company-wide Winter holiday shutdown Sabbaticals for 5-year and 10-year anniversaries #LI-Hybrid  #BI-Hybrid  #LI-GP1 Benchling welcomes everyone.  We believe diversity enriches our team so we hire people with a wide range of identities, backgrounds, and experiences.  We are an equal opportunity employer. That means we don’t discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We also consider for employment qualified applicants with arrest and conviction records, consistent with applicable federal, state and local law, including but not limited to the San Francisco Fair Chance Ordinance.   Please be aware that Benchling will never request personal information, payment, or sensitive details outside of Greenhouse or via email. All official communications will come from an @benchling.com email address or from an approved vendor alias. If you are contacted by someone claiming to represent Benchling and are unsure of their legitimacy, please reach out to us at recruiting-fraud-alert@benchling.com to verify the communication.  

Posted 30+ days ago

Cell Biology Scientist II, BioProduction R&D (Grand Island, NY)-logo
Cell Biology Scientist II, BioProduction R&D (Grand Island, NY)
Thermo Fisher ScientificGrand Island, New York
Work Schedule Standard (Mon-Fri) Environmental Conditions Able to lift 40 lbs. without assistance, Laboratory Setting Job Description Thermo Fisher Scientific Inc. is seeking a Scientist II who is highly motivated and high-reaching to join our outstanding research team in Grand Island. As a world-class leader in scientific research and innovation, Thermo Fisher Scientific provides an unparalleled environment for individuals who demonstrate strong work behaviors and an aim to make a significant impact. When you join us at Thermo Fisher Scientific, you’ll become part of a hard-working, driven team that shares your passion for exploration and discovery. With revenues in excess of $40 billion and an investment of over $1 billion per year in R&D, we give our people the resources and chances to create significant contributions to the world. Location: This is an onsite role in Grand Island, NY. Residency near Grand Island is required. No relocation assistance will be provided. Responsibilities: Designs experimental plans with guidance and conducts experiments, analyzes data, generates laboratory protocols, technical reports, and product summaries Works on problems of moderate scope where analysis of data requires an evaluation of various factors Troubleshoots and solves problems in the design/execution of development projects Exhibits creativity in selecting approaches and techniques for obtaining solutions Investigates new methods and technologies and maintains accurate lab notebook to support protection of intellectual property in accordance with relevant Thermo Fisher required standards Maintains knowledge of principles and theories through familiarity with opposing technologies and/or products and review of current scientific literature Presents data internally and contributes to external publications when appropriate Interacts with other internal departments (i.e., Business Development, Quality, Operations, Technical Services, and/or Marketing) Performs duties independently with guidance from manager Follows all company safety, training, and quality regulations (e.g., ISO compliance, GLP/GMP requirements, etc.) and procedures May be required to perform other related duties as the need arises and/or assigned Work in a laboratory environment and is required to lift up to 40 lbs Work safely with chemicals and hazardous materials Minimum Qualifications (must have): Bachelor’s degree with 2 plus years of experience or Master's degree in Biology, Biochemical Engineering, Biochemistry or other related field, or equivalent knowledge and experience Familiar with methods and techniques of small-scale mammalian cell culture Basic understanding of statistical analysis Demonstrated competence in data analysis Ability to identify and solve problems of moderate scope Excellent verbal and written communication skills and the ability to communicate scientific results in a clear, concise, & accurate manner Excellent organizational skills, including the ability to efficiently evaluate and balance multiple project tasks We are motivated to add a team-player with strong communication and interpersonal skills. If you have a degree in biochemistry, biology, chemical or biological engineering, or a related field, we would love to talk with you! Preferred Qualifications (nice to have): Understanding of scientific principles and shown proficiency in statistical design of experiments (DOE) Experience in research design and the evaluation of new techniques and procedures for manufacturing reagents, systems, products or technologies Prior industrial experience, particularly in process development and/or cell culture media formulation development Understanding of chemical, biochemical and physical interactions of cell culture media and reagent components Previous cell culture experience with cell lines used in protein production applications (e.g. CHO, HEK293, NS0) Previous experience with cell types used in cell therapy applications (e.g. T cells, MSC, ESC) or cell lines used in the production of viral vaccines (e.g. Vero, MRC-5, BHK) Familiarity with the operation of bench-top stirred tank bioreactors and related process development laboratory equipment as well as the scale-up of bioreactor and mixing systems Experience with high-throughput cell culture technologies (e.g. ambr15, ambr250) ​Our distributed team of more than 100,000 colleagues delivers an outstanding combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. Compensation and Benefits The salary range estimated for this position based in New York is $70,000.00–$88,000.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes: A choice of national medical and dental plans, and a national vision plan, including health incentive programs Employee assistance and family support programs, including commuter benefits and tuition reimbursement At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

Posted 1 week ago

I
Biology Teacher
Ivymax San Marino CorpIrvine, California
Benefits: 401(k) Paid time off Job Summary IvyMax Academy is a leading education service provider that prepares students exceptionally well for admission to top-tier universities and beyond. Since 2004, IvyMax has been delivering industry-best results, having helped thousands of students ace tests, develop strong leadership intelligence, and get admitted to great schools. The strength of IvyMax’s reputation and brand name is directly attributable to the quality and breadth of its products and services. We are excited to see the continued commitment from IvyMax’s management team to devote significant resources to enhancing IvyMax’s current offerings and developing new high-quality programs, products, and services that are responsive to the evolving market needs. IvyMax courses focus on quality instruction and test-taking strategies and techniques designed to help students achieve high scores on the tests and build strong fundamentals. IvyMax continuously recruits experienced teachers who generally teach in classes ranging from 5 to 20 students at the learning centers. Responsibilities and Duties · In-depth knowledge of AP Biology experience · Initiate, facilitate, and moderate classroom discussions. · Prepare course materials, such as syllabus, homework assignments, and handouts. · Plan, evaluate, and revise curricula, course content, course materials, and methods of instruction. · Maintain regularly scheduled office hours to advise and assist students. · Select and obtain materials such as textbooks, with the help of center staff members and the management team. · Collaborate with colleagues to address teaching issues. · Positively reinforce student self-confidence and self-esteem · Be organized and well-prepared for every lecture Qualifications and Skills · 4-year undergraduate degree (BA, BS) or higher related to the subject · 2+ year(s) of direct teaching/tutoring experience · Must have reliable transportation · Available weekday afternoons, evenings, and weekends Work Location: · IvyMax Learning Centers Job Type: Part-time Compensation: $40.00 - $65.00 per hour Since 2004, IvyMax has been delivering industry-best results, having helped thousands of students ace tests, develop strong leadership intelligence, write tremendous essays, and get admitted to great schools. IvyMax stands apart from other service providers because of our empowering values and holistic approach, the comprehensiveness of our high-quality offerings, and our industry-leading market results in both SAT® scores and college admissions. We offer SAT® Reasoning Test (SAT® I) prep. We offer SAT® Subject Test (SAT® II) prep. We offer expert college planning, applications, and admissions counseling (mentoring). We offer intelligent online learning technology. We have subject specialties for students with a strong interest in the arts or sciences, technology, engineering, and/or math (STEM). We offer preparation for academic competitions. We offer one-on-one and small group tutoring. We offer intellectually and emotionally stimulating international summer and winter programs. We work with top students and universities in the world. And we will work with you to develop a customized strategic plan to meet your needs.

Posted 2 weeks ago

T
Biology Tutor - Queens
Toolkit TutorsOzone Park, NY
About Us: Toolkit Tutors is a provider of in-school and after-school tutoring services, dedicated to enhancing student learning through personalized instruction and unwavering support. Job Description: Pay: $35 - $40/hr We are seeking a passionate and dedicated Biology Tutor to join our team in Queens. In this role, you will provide in-person tutoring to high school students during the day, focusing exclusively on Biology concepts and exam preparation. Compensation and Schedule: Target Launch Date: July 16, 2025 Schedule: Three 4-hour days each week Pay: $35 - $40 per hour, depending on experience Key Responsibilities: Conduct individualized tutoring sessions to help students master Biology concepts and prepare for the new Biology Regents exam. Develop and implement lesson plans tailored to the unique needs of each student. Monitor and assess student progress, providing regular feedback and support. Utilize a variety of teaching strategies and resources to keep students engaged and motivated. Collaborate with teachers and school staff to foster a supportive learning environment. Requirements Qualifications: Bachelor's degree (or currently pursuing a degree) in Education, Biology, or a related field. Previous experience tutoring or teaching high school Biology. Familiarity with the New York State Regents exams. Strong communication and interpersonal skills. Candidates who have been fingerprinted by the NYCDOE are strongly preferred. Benefits Benefits: Competitive hourly rate starting at $35-$40 per hour Opportunity to make a meaningful impact on students' academic and personal growth Supportive and collaborative work environment Paid professional development opportunities

Posted 30+ days ago

Research Scientist, Cell Biology-logo
Research Scientist, Cell Biology
NudgeSan Francisco, California
About Nudge Nudge’s goal is to help the brain work better by creating a generalized product that can precisely stimulate and image the brain, entirely non-invasively. We aim to achieve this by developing cutting-edge ultrasound technology to treat neurological and psychiatric disorders, like addiction, and eventually, creating a mainstream consumer device that can modulate mood, focus, sleep, and more. To realize those ambitions, we’re growing a scrappy, multidisciplinary, science and engineering team focused on making the best technology possible for interfacing with the whole brain, and a product that has the potential to improve people’s daily lives more than any other. About the team The Research Team at Nudge is innovating on multiple frontiers in neuroscience and neurotechnology, and is primarily focused on developing ultrasound-based neuromodulation to treat conditions like depression, chronic pain and addiction as well as enhance the wellbeing of healthy people. We’re also building the first scalable, portable hardware for noninvasive structural ultrasound-based imaging the quality of an MRI. The team is running human trials for neuromodulation and developing algorithms that will enable on-device imaging. About the role Develop methods for characterizing the mechanism of action of ultrasound on neural tissue Design and execute experiments in vitro to determine the impact of ultrasound on cellular properties and activity Explore optimization of the ultrasound parameter space for driving cellular activity and plasticity Translate in-vitro findings to human studies of neuromodulation About you 5+ years experience PhD or Postdoc in neuroscience, molecular/cellular biology, biomedical engineering or another science or engineering discipline Demonstrated history of exceptional contributions in your prior work experiences Experience in one or more of: Neural cell culture methods Human neural iPSC methods Calcium imaging, functional imaging analysis

Posted 1 week ago

Scientist, Computational Biology-logo
Scientist, Computational Biology
Cell Signaling TechnologyDANVERS, MA
Who we are… Cell Signaling Technology (CST) is a different kind of life sciences company, one founded, owned, and run by active research scientists, with the highest standards of product and service quality, technological innovation, and scientific rigor for over 20 years. We consistently provide fellow scientists around the globe with best-in-class products and services to fuel their quests for discovery. Helping researchers find new solutions is our main mission every day, but it's not our only mission. We're also dedicated to helping identify solutions to other problems facing our world. We believe that all businesses must be responsible and work in partnership with local communities, while seeking to minimize their environmental impact. That's why we joined 1% for the Planet as its first life science member, and have committed to achieving net-zero emissions by 2029. The role... Cell Signaling Technology (CST) is seeking a highly skilled Scientist, Computational Biologist to join the Computational Biology team within the Bioinformatics & Data Science department in the R&D organization. This role will focus on developing and applying computational approaches for immunology, BCR sequencing, proteomics, multi-omics integration, single-cell analysis, spatial biology, and epigenetics, ultimately driving scientific innovation. The successful candidate will actively collaborate with interdisciplinary teams within Bioinformatics & Data Science, including Computational Biology, Data Science, Bioinformatics Software Engineering, Informational Science, and Structural Biology. They will also work closely with other R&D departments, such as Proteomics and Molecular Biology, and cross-functional teams across the organization, including Marketing & Commercial, Data Engineering, and Lab Informatics. This position requires strong computational expertise, innovative problem-solving skills, and the ability to translate complex biological data into actionable insights. The ideal candidate will leverage diverse expertise from cross-functional teams to develop robust computational solutions, fostering scientific breakthroughs and advancing CST’s research objectives. You'll have the opportunity to... Develop and implement computational pipelines for BCR sequencing, single-cell analysis, spatial biology, epigenetics, and multi-omics data integration.  Design scalable bioinformatics workflows for high-throughput sequencing and multi-omics datasets.  Apply machine learning and statistical modeling to large-scale biological data.  Collaborate with immunologists, biologists, and data scientists to support CST’s research. Integrate computational methods with R&D initiatives, including Single Cell Technologies, Proteomics, and Molecular Biology.  Work with Bioinformatics, Data Science, Software Engineering, and Structural Biology teams to enhance data-driven discoveries.  Partner with Marketing, Commercial, Data Engineering, and Lab Informatics to apply computational insights strategically.  Maintain documentation and reproducibility standards.  Communicate findings through reports and publications. Who you are and what you bring to the team... Ph.D. in Computational Biology, Bioinformatics, Data Science, Immunology or a related field, with relevant postdoctoral and a minimum of 2 years of hands-on experience in the field. Postdoctoral experience may be considered as part of the required experience  Technical Expertise: Proficiency in programming languages such as Python, R, and Bash. Experience with bioinformatics tools for sequencing data, especially BCR sequencing and single-cell analysis.  Strong understanding of immunological data analysis and interpretation.  Hands-on experience in proteomics analysis and integrating multi-omics datasets.  Familiarity with machine learning applications in bioinformatics.  Experience working with cloud computing and high-performance computing (HPC) environments. Soft Skills: Strong problem-solving skills and ability to work independently.  Effective communication skills for interdisciplinary collaboration.  Ability to manage multiple projects and deadlines efficiently. Ideally, you have... Proficiency in software engineering best practices, including version control (Git), workflow automation, and continuous integration/deployment (CI/CD).  Experience working within an Agile development environment, applying methodologies to enhance collaboration and project efficiency.  Demonstrated experience in structural prediction and molecular modeling, particularly in the context of antibody-antigen interactions.  Familiarity with containerization and orchestration technologies (e.g., Docker, Kubernetes) for scalable and reproducible computational analyses.  Knowledge of data visualization techniques and tools for effectively presenting complex bioinformatics data. Physical Conditions/Physical Requirements... Cubicle on-site No wet lab work required  Low noise (virtual meetings, computer audio) Work area can be filled with collaborative discussion Requires the ability to sit for extended periods, use a computer keyboard and mouse, good vision and hearing for computer work/virtual meetings What we offer... At Cell Signaling Technology (CST), we recognize that people will always be our most important asset. Providing a safe, inclusive, and stimulating working environment that understands the importance of diversity, human dignity, and meaningful work is as important as establishing company policies that incorporate excellent health insurance and pay benefits. We recognize that the  development of people is the key to their happiness and thus ensure every employee has impactful discussions with their manager and develops actionable performance and professional development plans. Lastly, we are committed to engaging and supporting our employees in committees and philanthropy that benefit their local communities and environment through community investment programs. Benefits Medical (BCBS) and Dental (Delta Dental) plans paid at 90% Vision Insurance Life Insurance, Short and Long Term Disability Flexible Spending accounts 401(k) Plan with 6% match Tuition Reimbursement Generous PTO package Parental Leave Pet Insurance Employee Assistance Program Onsite Subsidized Cafeteria Free Parking Cell Signaling Technology (CST) is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. AGENCIES All resumes submitted by search firms/employment agencies to any employee at Cell Signaling Technology (CST) via email, the Internet, or in any form and/or method will be deemed the sole property of CST unless CST engaged such search firms/employment agencies for this position and a valid agreement with CST is in place. In the event a candidate who was submitted outside of the CST agency engagement process is hired, no fee or payment of any kind will be paid. If you are a California resident, more details on how we process your personal information can be found here.

Posted 3 weeks ago

Senior Director, Head of Protein Sciences and Structural Biology-logo
Senior Director, Head of Protein Sciences and Structural Biology
Psivant TherapeuticsBoston, Massachusetts
Position Summary We are seeking an exceptional and highly motivated leader for our protein sciences and structural biology group. This individual will play a critical role in advancing our pipeline of first-in-class drug candidates. The successful candidate will have a proven track record of success in small molecule drug discovery, a deep understanding of structural biology, biophysics, biochemistry and a passion for innovation. Responsibilities Lead and mentor a high-performing team of scientists in small molecule discovery, structural biology and in biophysical and biochemical strategies to advance programs. Enable small molecule drug discovery, from hit identification through lead optimization. Design and implement strategies for structure-based drug design, including X-ray crystallography, cryo-EM, and other relevant structural biology techniques. Collaborate with in-silico team to integrate structural biology and biophysical data to maximally leverage our unique computational advantage. Establish robust screening funnels and compound flows with project teams. Collaborate closely with other groups, including computational chemistry, medicinal chemistry, biology, and DMPK to advance drug discovery programs. Work with a cross-functional team to assess druggability and propose screening strategies for new targets. Stay abreast of the latest advances in small molecule discovery and structural biology ensuring that we implement the appropriate new technologies to enhance the group's capabilities to progress our drug pipeline. Represent Psivant at scientific conferences and meetings as a leader in structure-based drug discovery grounded in a deep understanding of the physical principles that govern biology. Contribute to scientific publications and patent applications. Requirements Ph.D. in biochemistry, structural biology, or a related field. Minimum 10 years of experience in small molecule drug discovery, with a strong emphasis on structural biology. A deeper understanding of biophysical and biochemical strategies to enable small molecule discovery is preferred. Demonstrated experience leading and managing drug discovery teams. Expertise in a wide range of structural biology and biophysical techniques, including X-ray crystallography, cryo-EM, and computational modeling. Strong understanding and application of medicinal chemistry principles to drug design. Excellent communication and interpersonal skills. Ability to thrive in a fast-paced and collaborative cross functional environment. About Psivant Psivant Therapeutics is creating better therapeutics through an integrated molecular design paradigm that leverages best-in-class physics-based and AI technologies honed through decades of research and innovation. Our focus is first-in-class inflammation and immunology (I&I) small molecule therapeutics. We have assembled a diverse team with extensive experience across disciplines ranging from physics and computer science to chemistry, biology, biochemistry, and structural biology. This continuum of complementary skills drives our scientific vision to deliver meaningful therapeutics to patients in need. We are patient-inspired, perseverant, synergistic, supportive, intrepid, and inclusive. If you’re passionate about advancing medicine in a fast-paced, innovative environment, and eager to contribute to a team that blends advanced computation with drug discovery, Psivant might be the perfect fit for you. At Psivant, we are a lean, high-performing team dedicated to pushing boundaries and achieving growth—both personally and scientifically. We seek individuals who are smart, collaborative, and thrive in a dynamic, early-stage biotech environment. Individuals joining Psivant can look forward to the following: · Competitive salary and benefits package including 401k match · Opportunity to make a significant impact on the development of novel therapeutics. · Work with a talented and passionate team of scientists · Be a part of a cutting-edge company that is revolutionizing drug discovery. Learn more about our story at https://psivant.com/company/our-story/ .

Posted 1 day ago

Biology/Chemistry Tutors-logo
Biology/Chemistry Tutors
Next Level TutoringAllentown, Pennsylvania
Job Description Nexel Level Tutoring, LLC. Emmaus-Macungie is looking for tutors for high school and college level Biology and Chemistry. Areas include East Penn, Parkland, Northwestern, Allentown, Bethlehem, Southern Lehigh, Salisbury, and Upper Perkiomen school districts. We are looking for tutors who have some of the experience listed below : Certified teachers for Elementary, Middle School or High School College upperclassmen education majors with tutoring experience Professionals who are subject matter experts and have the gift of teaching and mentoring Minimum Requirements for tutoring positions: Bachelor's degree or college students in the junior or senior year 1-year tutoring or teaching experience preferred Understanding local curriculum Willingness to travel up to 30 mins to student assignments Organized, reliable and dependable Have basic computer and Internet skills Pay rate: $22-27 per hour Type: Part-time/Contract positions We provide one-to-one-tutoring in the home, customized to the unique needs of each individual student. We re passionate about education and we strive to make learning fun and effective! If you are passionate about education and have a desire to help students reach their educational goals please apply now! Company Description Since 2000, TD has been the trusted choice for private tutoring services around the world. We work with more than 17,000 tutors in 15+ countries, so we can bring our vision of better tutoring to students everywhere.

Posted 1 day ago

Online Academic Tutor - Biology-logo
Online Academic Tutor - Biology
The Princeton ReviewManhattan, NY
Are you looking to make an impact through a rewarding, flexible part-time gig that you can do from home? The Princeton Review is looking to bring on additional online Academic Tutors for rewarding work that can make a difference. Major Responsibilities: Tutor students in our online classroom in a dynamic and supportive manner Customize lesson plans to meet students’ needs and keep them engaged in material. Familiarize yourself with a student’s school curriculum Model professionalism and accountability at all times by showing up to tutoring sessions on time, replying to students and parents in a timely manner, and holding students accountable for assignments. Create an open, safe, and positive learning environment. Regularly documenting student progress and communicating this progress with student and parents. Education, Background, Experience & Qualifications: Bachelor’s degree completed or in progress Confident and engaging discussion leader High school level expertise in academic subject matter evident through educational background or work-related experience. Excellent verbal and written communication skills Availability after school and/or weekends. Summer daytime availability a plus. Applicants must pass a qualifying exam Access to a reliable internet connection and computer in a reliably quiet location Experience with one-on-one tutoring required. Experience teaching online preferred. Why you want to teach for The Princeton Review: Competitive hourly teaching rates Flexible hours: work when you’re available to work Paid training Performance and merit-based raises and bonuses You can work remotely from most locations with a stable internet connection within the US Work for a company with a long-standing reputation in the education industry with opportunities for growth. Other Subjects Needed: Chemistry Compensation: Pay: $16-$26 per hour, based on credentials and geographic location The company does not provide benefits for this position. Applications accepted on an ongoing basis. Please note that the above-referenced position can be performed anywhere in the United States except in the following states: Arkansas, Hawaii, Idaho, Mississippi, New Mexico, North Dakota, Rhode Island, South Dakota and Wyoming. About The Princeton Review: The Princeton Review is a leading tutoring, test prep, and college admission services company. Every year, it helps millions of students bound for college and graduate school to achieve their education and career goals through online and in-person courses delivered by a network of more than 4,000 teachers and tutors, online resources, and its more than 150 print and digital books published by Penguin Random House. The company’s Tutor.com brand is one of the largest online tutoring services in the U.S. It comprises a community of thousands of tutors who have delivered more than 19 million one-to-one tutoring sessions. The Princeton Review is headquartered in New York, NY. Follow the company on LinkedIn , YouTube and Instagram . The Princeton Review is an equal employment opportunity employer. The Princeton Review’s policy is not to discriminate against any applicant or employee based on race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, marital status, disability, military status, genetic information, or any other basis protected by applicable law. The Princeton Review also prohibits harassment of applicants or employees based on any of these protected categories. It is also The Princeton Review’s policy to comply with all applicable laws respecting consideration of unemployment status in making hiring decisions. The Princeton Review is a drug-free workplace. Pursuant to, and consistent with, any applicable state or local laws, such as the Los Angeles Fair Chance Initiative for Hiring Ordinance, Los Angeles County Fair Chance Ordinance for Employers, New York City Fair Chance Act, Philadelphia’s Fair Chance Hiring Law, and San Francisco Fair Chance Ordinance, The Princeton Review will consider for employment qualified applicants with arrest and conviction records. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Review the Privacy Policy for California Employees, Job Applicants, and Independent Contractors

Posted 3 weeks ago

St. Jude Children's Research Hospital logo
Postdoctoral Research Associate - Structural Biology
St. Jude Children's Research HospitalMemphis, Tennessee

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Job Description

A postdoctoral research associate position is available in the lab of Tanja Mittag in the Department of Structural Biology.

Project Description:

The Mittag laboratory invites applications for a Postdoctoral Research Associate Position to work on the biophysics of sequence–structure–function relationships of intrinsically disordered protein regions (IDRs). IDRs use different types of sequence-encoded grammars, and these are often tied to their subcellular localization and the biological processes they are involved in. We have extensively characterized how the molecular grammar of prion-like low-complexity domains encode conformational preferences and give rise to condensates with specific emergent properties (e.g., Martin et al. Science 2020, Bremer et al. Nat Chem 2022, Farag et al. Nat Commun 2023; Alshareedah et al. Nat Physics 2024; Posey et al JACS 2024). In this project, we will define sequence-encoded conformational preferences, driving force for phase separation and emergent properties of other types of IDR sequences.

Position Responsibilities:

The successful candidate will help shape the direction of the research and will use in vitro biophysical and biochemical studies to characterize the conformational properties of IDRs and the properties of the condensates they form. The candidate will interface with trainees and staff scientists in the Mittag lab, and with collaborators in a highly collaborative, interdisciplinary environment that will support their career development. 

Minimum Education and/or Training:

The successful candidate should have a Ph.D. in biophysics or a related discipline. The candidate should demonstrate an academic record of excellence, and a strong interest in the growing field of biomolecular condensates.

Special Skills, Knowledge, and Abilities:

Experience with quantitative biophysical techniques such as NMR spectroscopy and/or small-angle X-ray scattering is required to capitalize on the opportunities of this project.

About the lab and St. Jude:

The successful candidate will join a highly collaborative laboratory focused on elucidating the biophysics, biochemistry and function of condensates in the Department of Structural Biology, with access to state-of-the-art instrumentation and expertise in the Department of Structural Biology and across the hospital.

St. Jude Children’s Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The first and only National Cancer Institute (NCI)-designated Comprehensive Cancer Center devoted solely to children. Our 300 faculty work across the spectrum of basic, translational, clinical, and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine. St. Jude is ranked on Fortune Magazine’s “Best Workplaces in Health Care & Biopharma” and Glassdoor’s “Best Places to Work,” and is located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food and culture.

We are in pursuit of the brightest minds in biomedical sciences, individuals poised to contribute to our research progress. Other than access to top-quality scientists and mentors, as a postdoctoral trainee at St. Jude, you will have:

  • A Blend of Academic Freedom and Industrial Efficiency: Access to shared resources and facilities led by expert scientists, coupled with cutting-edge technology, accelerates research productivity.

  • Customized Professional and Career Growth: Experience specifically designed programs to enhance professional growth and career readiness empowering postdocs for success beyond their training. This includes access to grant writing workshops, individual development plans, teaching and mentoring opportunities, non-research career advancement programs, professional development allowance, and so much more.

  • Competitive Compensation: Embark on your journey with a competitive salary starting at $72,500 a year, comprehensive benefits and generous relocation assistance, reflecting our commitment to recognize and invest in talent.

  • A Sense of Community: St. Jude fosters a vibrant postdoc community that supports a well-balanced life. A dynamic environment promotes connections and camaraderie among postdocs from all backgrounds.

                             

St. Jude is an Equal Opportunity Employer

No Search Firms

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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