Management Jobs 2026 (Now Hiring) – Smart Auto Apply

Job Description

The Portfolio & Program Management Platform Business Owner, Director, is an individual contributor leadership role within the Portfolio & Program Management (PPM) organization and newly formed Center of Excellence, serving as the business owner for platforms and AI-enabled capabilities that support PPM and the broader Transactions, Alliances, and Portfolio Management (TAPM) organization. The incumbent owns the business strategy, governance, requirements, adoption, and value realization for PPM/TAPM technology platforms and AI-enabled capabilities, in partnership with IT and other enabling functions responsible for technical delivery, architecture, security, and support. This role leads cross-functional business efforts to evolve project and portfolio management capabilities, strengthen data governance, and advance an integrated, AI-ready planning and reporting environment. 

Key Duties and Responsibilities

• Partner with TAPM leadership and IT to shape and execute the business roadmap for PPM/TAPM technology platforms and AI-enabled capabilities, driving delivery of capabilities that enhance portfolio planning, decision-making, and operational effectiveness 

• Serve as business owner for the PPM project management platform(s), including MS Project Server Subscription Edition as the business system of record for functional and integrated project plans 

• Lead business ownership of AI tools and use cases across PPM and TAPM to improve reporting, analytics, automation, and process efficiency 

• Ensure project and portfolio management data effectively supports portfolio reporting, resource planning, financial planning, and enterprise decision-making 

• Lead cross-functional business efforts to define requirements, evaluate options, prioritize needs, and support selection of future-state project management and portfolio technology solutions in partnership with IT and other delivery partners 

• Coordinate integration across project plans, portfolio data, resources, and financials to support a more connected planning environment and improved data quality 

• Define and maintain business processes for platform governance, data governance, user support, issue triage, adoption, and continuous improvement, while partnering with IT for technical administration and support 

• Partner with TAPM leaders and cross-functional stakeholders to align priorities, influence decisions, and support adoption of systems, tools, and process changes 

• Oversee business ownership and effective use of other department technologies, including collaboration tools such as SharePoint, as applicable, with technical administration supported by appropriate enabling functions 

Knowledge and Skills

• Broad understanding of project and portfolio management systems, including direct experience with MS Project; familiarity with other industry-relevant platforms preferred 

• Understanding of how project planning data supports portfolio reporting, resource planning, financial planning, and portfolio decision-making 

• Experience serving as a business owner or business product owner for enterprise platforms, including governance, requirements definition, adoption, user support, issue triage, and partnership with IT delivery teams 

• Knowledge of AI and automation applications in business processes; experience with Power BI or similar reporting and visualization tools preferred 

• Knowledge of data governance, data quality, and stewardship practices 

• Pharmaceutical drug discovery and development expertise across multiple disciplines 

• Strong collaboration, communication, organizational, and problem-solving skills, with the ability to influence stakeholders across a matrixed organization 

Education and Experience

• Typically requires a bachelor’s degree in Business, Life Sciences, Program/Portfolio Management, Information Systems, Data Science, or a related field 

• Typically requires 12 years of experience, or the equivalent combination of education and experience 

• Relevant experience in the pharmaceutical, biotechnology, or related industry supporting portfolio management, program management, business systems, or operations is required 

• Experience leading cross-functional initiatives and working with senior stakeholders is required 

• Supervisory or people leadership experience is preferred but not required 

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 1.    Hybrid: work remotely up to two days per week; or select2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. 

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com