Program Manager Jobs 2026 (Now Hiring) – Smart Auto Apply

InterSystems is a global leader in healthcare data management and interoperability, providing mission-critical technology that powers hospitals, health systems, and national infrastructures worldwide. Our products underpin trusted healthcare and financial systems where performance, availability, and security are non-negotiable.

As a Senior Program Manager, you lead large-scale, complex, cross-functional initiatives across product, engineering, cloud, and AI. You operate across organizational boundaries, translating objectives aligned to corporate strategy into coordinated, measurable outcomes. You support and operationalize the security strategy across the portfolio, ensuring effective execution through structured programs.

Security and performance are horizontal capabilities across our stack. You partner with product, engineering, and architecture to maintain consistent execution across the portfolio.

Key Characteristics

• Thrives in high ambiguity, competing priorities
• Owns outcomes at a program level
• Connects strategy to execution (systems thinker)
• Influences without authority
• Execution-focused; manages complexity
• Communicates clearly across technical and business audiences

Key Responsibilities

• Program Strategy, Execution & Delivery
  • Execute against existing program direction and strategic priorities, incorporating security and performance, and influencing future prioritization and execution
  • Translate program strategy into execution plans across multiple teams and projects
  • Lead concurrent projects to deliver program objectives
  • Coordinate execution with program managers across cloud, database, interoperability, HealthShare, and AI-enabled systems
  • Align scope, priorities, and dependencies to enable delivery
• Cross-Functional Leadership & Stakeholder Management
  • Orchestrate work across product, engineering, architecture, compliance, and operations
  • Serve as integration point for dependencies, timelines, and deliverables
  • Manage senior stakeholders, including executive engagement
  • Communicate progress, risks, and decisions to support leadership action
  • Run structured updates and program reviews to maintain alignment
• Program Performance, Health & Continuous Improvement
  • Monitor program performance and health against established KPIs, objectives, and milestones; contribute to KPI refinement
  • Manage risks, issues, and dependencies; escalate when needed
  • Maintain clear program visibility and enforce accountability
  • Improve execution, coordination, and operational effectiveness

Qualifications

• Bachelor’s degree in Computer Science, Business, Engineering, or related field; advanced degree preferred
• 10+ years leading large-scale, complex, cross-functional programs
• Strong fundamentals in planning, scheduling, dependency and risk management
• Experience managing performance to KPIs and driving accountability
• Experience in cloud, healthcare, or enterprise technology environments preferred
• Proven ability to influence senior stakeholders without direct authority
• Strong communication and leadership skills
• PMP or equivalent certification a plus
• Experience using AI-assisted tools (e.g. copilots, summarisation tools, or chatbots) with an ability to critically evaluate and verify AI-generated outputs
• Demonstrated ability to learn, evaluate, adapt to, propose and implement AI-augmented workflows in order to continually enhance your own, and the team’s productivity

We are an equal-opportunity employer and do not discriminate because of race, color, religion, sex, national origin, ancestry, marital status, veteran status, age, disability, sexual orientation or gender identity or expression or any other legally protected category. InterSystems is an E-Verify Employer in the United States.

About InterSystems

InterSystems, a creative data technology provider, delivers a unified foundation for next-generation applications for healthcare, finance, manufacturing, and supply chain customers in more than 80 countries. Our data platforms solve interoperability, speed, and scalability problems for large organizations around the globe to unlock the power of data and allow people to perceive data in imaginative ways. Established in 1978, InterSystems is committed to excellence through its 24×7 support for customers and partners around the world. Privately held and headquartered in Boston, Massachusetts, InterSystems has 38 offices in 28 countries worldwide. For more information, please visit InterSystems.com.

AI Disclaimer

InterSystems may use AI tools for its internal operations including administrative tasks during recruitment (e.g., organizing candidate information).  InterSystems’ approach to AI is guided by the InterSystems Responsible AI Guidelines. AI is not used to make or influence hiring decisions. All decisions are made by InterSystems employees.

Candidates may use AI for CV or interview preparation, provided materials are truthful and reflect their own experience.  AI tools and third-party transcription services must not be used during interviews or assessments.

Please note that the use of wearable technology, including any AI-related tools or other technology-connected devices (such as META or Google smart glasses and/or wearables, and/or any similar devices), isstrictly prohibitedduring the interview and screening process with InterSystems.  Any applicant who requires a wearable device or any type of technology support during the interview process as a reasonable accommodation under the ADA or applicable state or country laws and regulations must contact the InterSystems Human Resources Departmentprior to attending or participating in any interview or screening process.