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At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care throughout the patient journey. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Summary:

As a Senior Scientist, you will contribute to sustaining operations by troubleshooting existing manual and automated methods, as well as assisting with performance qualifications for new automated methods and instruments. You should be an energetic and hands-on individual who has the technical background to identify the source(s) of issues and find effective solutions for issue mitigation and sample rescue. Your work will contribute to a new generation of genomics-based precision medicine products in immuno-oncology and cancer clinical trials, diagnostics, and therapeutics being used by pharma, biotech, hospitals and clinicians.

Responsibilities:

• Collaborate with the Operations, Product Development, Tech Transfer and Automation team members for implementation and troubleshooting of manual and automated methods.
• Provide timely support and training for Operations end-users.
• Plan and execute performance qualification tests for new methods and instruments.
• Evaluate and qualify new reagents and consumables.
• Support documentation efforts for laboratory procedures and equipment qualifications.
• Develop new methods and protocols for manual sample recovery.
• Participate in group meetings and present results.
• Use effective two-way communication to create and maintain a collaborative working environment.
• Support and ensure compliance with all department and company policies and procedures

Education and Experience:

• PhD or MS with a minimum of 4 years of experience, or BS with a minimum of 8 years of experience.
• Minimum of 2 years of laboratory experience with DNA/RNA, NGS technology and lab automation.
• Strong written and verbal communication skills required.
• Excellent organization and troubleshooting skills required.
• Flexibility, multitasking, and teamwork are required to support operations personnel.
• Experience using root cause analysis tools and techniques highly desired.
• Experience in biotech and clinical labs is highly desired.
• Strong desire to work in a demanding, high-energy, hands-on, and fast-paced environment.

The hiring range for this position is $132,000 to $165,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

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